Clinical pharmacokinetics and pharmacodynamics of propofol

MM Sahinovic, MMRF Struys, AR Absalom - Clinical pharmacokinetics, 2018 - Springer
Propofol is an intravenous hypnotic drug that is used for induction and maintenance of
sedation and general anaesthesia. It exerts its effects through potentiation of the inhibitory …

Effects of anesthesia on cerebral blood flow, metabolism, and neuroprotection

AM Slupe, JR Kirsch - Journal of Cerebral Blood Flow & …, 2018 - journals.sagepub.com
Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

Cerebral blood flow autoregulation and dysautoregulation

WM Armstead - Anesthesiology clinics, 2016 - anesthesiology.theclinics.com
Cerebral autoregulation is a homeostatic process that regulates and maintains cerebral
blood flow (CBF) constant across a range of blood pressures. The original concept was …

Cardiac output and cerebral blood flow: the integrated regulation of brain perfusion in adult humans

L Meng, W Hou, J Chui, R Han, AW Gelb - Anesthesiology, 2015 - pubs.asahq.org
Cerebral blood flow (CBF) is rigorously regulated by various powerful mechanisms to
safeguard the match between cerebral metabolic demand and supply. The question of how …

Intraoperative motor evoked potential monitoring–a position statement by the American Society of Neurophysiological Monitoring

DB Macdonald, S Skinner, J Shils, C Yingling - Clinical Neurophysiology, 2013 - Elsevier
The following intraoperative MEP recommendations can be made on the basis of current
evidence and expert opinion:(1) Acquisition and interpretation should be done by qualified …

Regulation of cerebral autoregulation by carbon dioxide

L Meng, AW Gelb - Anesthesiology, 2015 - pubs.asahq.org
Cerebral autoregulation describes a mechanism that maintains cerebral blood flow stable
despite fluctuating perfusion pressure. Multiple nonperfusion pressure processes also …

MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis

JM Serrador, PA Picot, BK Rutt, JK Shoemaker… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—The relationship between middle cerebral artery (MCA) flow
velocity (CFV) and cerebral blood flow (CBF) is uncertain because of unknown vessel …

Cerebral hyperperfusion syndrome

WNKA van Mook, RJMW Rennenberg… - The Lancet …, 2005 - thelancet.com
Cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy is characterised by
ipsilateral headache, hypertension, seizures, and focal neurological deficits. If not treated …

Monitoring of cerebral autoregulation in head-injured patients

M Czosnyka, P Smielewski, P Kirkpatrick, DK Menon… - Stroke, 1996 - Am Heart Assoc
Background and Purpose Disturbed cerebral autoregulation has been reported to correlate
with an unfavorable outcome after head injury. Using transcranial Doppler ultrasonography …

Assessment of cerebral pressure autoregulation in humans-a review of measurement methods

RB Panerai - Physiological measurement, 1998 - iopscience.iop.org
Assessment of cerebral autoregulation is an important adjunct to measurement of cerebral
blood flow for diagnosis, monitoring or prognosis of cerebrovascular disease. The most …