Rationale: Lung injury caused by a ventilator results from nonphysiologic lung stress
(transpulmonary pressure) and strain (inflated volume to functional residual capacity ratio) …

Protective ventilation with low tidal volume has been shown to reduce morbidity and
mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress …

Direct measurement of lung volume, ie functional residual capacity (FRC) has been
recommended for monitoring during mechanical ventilation. Mostly due to technical reasons …

Background Individualized positive end-expiratory pressure (PEEP) guided by dynamic
compliance improves oxygenation and reduces postoperative atelectasis in nonobese …

Objective To evaluate the efficacy of different lung recruitment maneuvers using electric
impedance tomography. Design and setting Experimental study in animal model of acute …

Objectives: Airway closure is involved in adverse effects of mechanical ventilation under
both general anesthesia and in acute respiratory distress syndrome patients. However …

Objective: The common denominator in most forms of ventilator-induced lung injury is an
intense inflammatory response mediated by neutrophils. PET with [18 F] fluoro-2-deoxy-D …

Introduction Airway dysfunction in patients with the Acute Respiratory Distress Syndrome
(ARDS) is evidenced by expiratory flow limitation and dynamic hyperinflation. These …

Purpose To determine reciprocal and synergistic effects of acute intracranial hypertension
and ARDS on neuronal and pulmonary damage and to define possible mechanisms …

Purpose Clinical applications of quantitative computed tomography (qCT) in patients with
pulmonary opacifications are hindered by the radiation exposure and by the arduous …