Trachoma

HR Taylor, MJ Burton, D Haddad, S West, H Wright - The Lancet, 2014 - thelancet.com
Trachoma is the most common infectious cause of blindness. Repeated episodes of
infection with Chlamydia trachomatis in childhood lead to severe conjunctival inflammation …

Epidemiology and control of trachoma: systematic review

VH Hu, EM Harding‐Esch, MJ Burton… - Tropical Medicine & …, 2010 - Wiley Online Library
Trachoma is the commonest infectious cause of blindness. Recurrent episodes of infection
with serovars A–C of Chlamydia trachomatis cause conjunctival inflammation in children …

Azithromycin versus doxycycline for the treatment of genital chlamydia infection: a meta-analysis of randomized controlled trials

FYS Kong, SN Tabrizi, M Law… - Clinical Infectious …, 2014 - academic.oup.com
Background. There has been recent debate questioning the efficacy of azithromycin for the
treatment of urogenital chlamydia infection. We conducted a meta-analysis to compare the …

Trachoma

HR Wright, A Turner, HR Taylor - The Lancet, 2008 - thelancet.com
Trachoma is a keratoconjunctivitis caused by ocular infection with Chlamydia trachomatis.
Repeated or persistent episodes lead to increasingly severe inflammation that can progress …

Pharmacokinetic considerations regarding the treatment of bacterial sexually transmitted infections with azithromycin: a review

FYS Kong, P Horner, M Unemo… - Journal of Antimicrobial …, 2019 - academic.oup.com
Rates of bacterial sexually transmitted infections (STIs) continue to rise, demanding
treatments to be highly effective. However, curing infections faces significant challenges due …

Development and evaluation of a next-generation digital PCR diagnostic assay for ocular Chlamydia trachomatis infections

CH Roberts, A Last, S Molina-Gonzalez… - Journal of clinical …, 2013 - Am Soc Microbiol
Droplet digital PCR (ddPCR) is an emulsion PCR process that performs absolute
quantitation of nucleic acids. We developed a ddPCR assay for Chlamydia trachomatis …

Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking …

L Kari, WM Whitmire, DD Crane… - The Journal of …, 2009 - journals.aai.org
A vaccine is likely the most effective strategy for controlling human chlamydial infections.
Recent studies have shown immunization with Chlamydia muridarum major outer …

Prospects for the control of neglected tropical diseases by mass drug administration

HL Smits - Expert Review of Anti-infective Therapy, 2009 - Taylor & Francis
The prospects for the control of neglected tropical diseases, including soil-transmitted
helminthiasis, shistosomiasis, lymphatic filariasis, onchocerciasis and trachoma, through …

Trachoma: an overview

MJ Burton - British medical bulletin, 2007 - academic.oup.com
Trachoma is the most common infectious cause of blindness worldwide. It afflicts some of the
poorest regions of the globe, predominantly in Africa and Asia. The disease is initiated in …

[HTML][HTML] Progress to eliminate trachoma as a public health problem in Amhara National Regional State, Ethiopia: results of 152 population-based surveys

AEP Stewart, M Zerihun, D Gessese… - The American journal …, 2019 - ncbi.nlm.nih.gov
At baseline in 2006, Amhara National Regional State, Ethiopia, was the most trachoma-
endemic region in the country. Trachoma impact surveys (TIS) were conducted in all districts …