[HTML][HTML] Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania: an emerging public health concern

L Muri, A Gamell, AJ Ntamatungiro, TR Glass… - Aids, 2017 - journals.lww.com
Objective: To investigate the prevalence and determinants of virologic failure and acquired
drug resistance-associated mutations (DRMs) in HIV-infected children and adolescents in …

[HTML][HTML] Virological suppression and clinical management in response to viremia in South African HIV treatment program: a multicenter cohort study

LE Hermans, S Carmona, M Nijhuis… - PLoS …, 2020 - journals.plos.org
Background Uptake of antiretroviral treatment (ART) is expanding rapidly in low-and middle-
income countries (LMIC). Monitoring of virological suppression is recommended at 6 months …

Cohort profile: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO)-A prospective HIV cohort in rural Tanzania.

E Letang, AV Kalinjuma, TR Glass, A Gamell… - Swiss medical …, 2017 - boris.unibe.ch
BACKGROUND The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) is a single-
site, open and ongoing prospective cohort of people living with human immunodeficiency …

[HTML][HTML] Decentralization of viral load testing to improve HIV care and treatment cascade in rural Tanzania: observational study from the Kilombero and Ulanga …

D Mnzava, J Okuma, R Ndege, N Kimera… - BMC Infectious …, 2023 - Springer
Introduction Monitoring HIV viral load (HVL) in people living with HIV (PLHIV) on
antiretroviral therapy (ART) is recommended by the World Health Organization …

Transitioning to dolutegravir in a programmatic setting: virological outcomes and associated factors among treatment-naive patients with HIV-1 in the Kilombero and …

AJ Ntamatungiro, A Eichenberger… - Open Forum …, 2023 - academic.oup.com
Background Virological outcome data after programmatic transition from non-nucleoside
reverse transcriptase inhibitor (NNRTI)-based to dolutegravir (DTG)-based antiretroviral …

Age-related comorbidities and mortality in people living with HIV in rural Tanzania

S Albrecht, FC Franzeck, H Mapesi, C Hatz… - Aids, 2019 - journals.lww.com
Objective: Causes of morbidity and mortality of people living with HIV are changing with
access to antiretroviral therapy and increased life expectancy. Age-related data on …

Understating the barriers to achievement of the UNAIDS 90–90–90 goal in Tanzania using a population-based HIV impact assessment survey 2016–2017

Y Wang, S Kiwuwa-Muyingo, DT Kadengye - AIDS care, 2022 - Taylor & Francis
ABSTRACT The Joint United Nations Programme on HIV/AIDS (UNAIDS) and partners
launched the 90–90–90 targets. We used Tanzania HIV Impact Survey (THIS) data in 2017 …

[HTML][HTML] Virologic status and pattern of drug resistance mutation among ART-experienced HIV-infected patients in Butuo County, China

M Chen, M Wu, L Zeng, Y Zhang, M Huobu-Mo… - Journal of Global …, 2023 - Elsevier
Objectives To assess the virological outcomes, prevalence of HIV drug resistance mutation
(DRM), and correlates in Butuo County. Methods We conducted a cross-sectional study …

[HTML][HTML] High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania–A prospective cohort study

RE Bircher, AJ Ntamatungiro, TR Glass, D Mnzava… - PLoS …, 2020 - journals.plos.org
Background Poor adherence to antiretroviral drugs and viral resistance are the main drivers
of treatment failure in HIV-infected patients. In sub-Saharan Africa, avoidance of treatment …

[HTML][HTML] CRF08_BC subtype is more prone to ART failure and new generation NNRTI-resistance under long-term first line ART

M Wu, Y Dong, L Zeng, Y Lin, L Yao, Y Zhang… - International Journal of …, 2024 - Elsevier
Objective To investigate the characteristics of drug resistance mutations (DRMs) and their
contextual influence on drug susceptibility in CRF07_BC and CRF_08BC subtypes …