Microfluidic manufacture of lipid-based nanomedicines

K Osouli-Bostanabad, S Puliga, DR Serrano, A Bucchi… - Pharmaceutics, 2022 - mdpi.com
Nanoparticulate technologies have revolutionized drug delivery allowing for passive and
active targeting, altered biodistribution, controlled drug release (temporospatial or triggered) …

Effective degradation of COVID-19 related drugs by biochar-supported red mud catalyst activated persulfate process: Mechanism and pathway

Z Guo, Y Zhang, S Gan, H He, N Cai, J Xu… - Journal of Cleaner …, 2022 - Elsevier
With the global spread of the COVID-19 pandemic, the water pollution caused by extensive
production and application of COVID-19 related drugs has aroused growing attention …

Permeation enhancers loaded bilosomes for improved intestinal absorption and cytotoxic activity of doxorubicin

AA Sultan, GA Saad, GM El Maghraby - International Journal of …, 2023 - Elsevier
The clinical utility of doxorubicin is compromised due to dose related toxic side effects and
limited oral bioavailability with no oral formulation being marketed. Enhancement of …

Bilosomes as effective delivery systems to improve the gastrointestinal stability and bioavailability of epigallocatechin gallate (EGCG)

L Wang, X Huang, H Jing, C Ma, H Wang - Food research international, 2021 - Elsevier
Epigallocatechin gallate (EGCG) has a variety of biological activities, but exhibits poor
stability and low bioavailability. In this study, EGCG bilosome was prepared and …

Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation, in vitro characterization, and in vivo …

AA Nemr, GM El-Mahrouk, HA Badie - Drug delivery, 2022 - Taylor & Francis
Agomelatine (AGO) is a dual-functional drug. It uses as an antidepressant when orally
administrated and antiglaucomic when topically applied to the eye. This study aimed to …

Spanlastics a novel nanovesicular carrier: its potential application and emerging trends in therapeutic delivery

MD Ansari, Z Saifi, J Pandit, I Khan, P Solanki… - AAPS …, 2022 - Springer
Nanotechnology-based drug delivery system has played a very crucial role in overpowering
the tasks allied with the conventional dosage form. Spanlastics, an elastic nanovesicle with …

Bilosomes as nanocarriers for the drug and vaccine delivery against gastrointestinal infections: Opportunities and challenges

E Zarenezhad, M Marzi, HT Abdulabbas… - Journal of Functional …, 2023 - mdpi.com
The gastrointestinal tract (GIT) environment has an intricate and complex nature, limiting
drugs' stability, oral bioavailability, and adsorption. Additionally, due to the drugs' toxicity and …

[HTML][HTML] Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment

A Zafar, NK Alruwaili, SS Imam, NH Alotaibi… - Saudi Pharmaceutical …, 2021 - Elsevier
Abstract Aim Diabetic (type-2) is a metabolic disease characterized by increased blood
glucose level from the normal level. In the present study, apigenin (AG) loaded lipid vesicles …

Development of surface modified bilosomes for the oral delivery of quercetin: Optimization, characterization in-vitro antioxidant, antimicrobial, and cytotoxicity study

NK Alruwaili, A Zafar, OA Alsaidan, M Yasir… - Drug Delivery, 2022 - Taylor & Francis
Quercetin (QT) is a flavonoid that exhibits anti-oxidant and chemo-preventive activity. This
research work aimed to develop surface-modified bilosomes (BS) of QT. The BS was …

Chitosan coated luteolin nanostructured lipid carriers: optimization, in vitro-ex vivo assessments and cytotoxicity study in breast cancer cells

SJ Gilani, M Bin-Jumah, M Rizwanullah, SS Imam… - Coatings, 2021 - mdpi.com
In the present study, luteolin (LTN)-encapsulated chitosan (CS) coated nanostructured lipid
carriers (NLCs) were formulated using the melt emulsification ultrasonication technique …