[HTML][HTML] Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
[HTML][HTML] Blood-brain barrier dysfunction amplifies the development of neuroinflammation: understanding of cellular events in brain microvascular endothelial cells for …
F Takata, S Nakagawa, J Matsumoto… - Frontiers in cellular …, 2021 - frontiersin.org
Neuroinflammation is involved in the onset or progression of various neurodegenerative
diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
[HTML][HTML] Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates
J Rostami, T Mothes, M Kolahdouzan… - Journal of …, 2021 - Springer
Background Alzheimer's disease (AD) and Parkinson's disease (PD) are characterized by
brain accumulation of aggregated amyloid-beta (Aβ) and alpha-synuclein (αSYN) …
brain accumulation of aggregated amyloid-beta (Aβ) and alpha-synuclein (αSYN) …
[HTML][HTML] Molecular mechanisms of neuroinflammation in aging and Alzheimer's disease progression
FL Andronie-Cioara, AI Ardelean… - International journal of …, 2023 - mdpi.com
Aging is the most prominent risk factor for late-onset Alzheimer's disease. Aging associates
with a chronic inflammatory state both in the periphery and in the central nervous system, the …
with a chronic inflammatory state both in the periphery and in the central nervous system, the …
Aging hallmarks and progression and age-related diseases: a landscape view of research advancement
Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …
[HTML][HTML] Aging Process and Related Diseases
The aging process is a complex biological phenomenon that results in the gradual decline of
physiological function and an increased risk of age-related diseases. While aging is a …
physiological function and an increased risk of age-related diseases. While aging is a …
[HTML][HTML] Dysregulation of systemic immunity in aging and dementia
J Lutshumba, BS Nikolajczyk… - Frontiers in Cellular …, 2021 - frontiersin.org
Neuroinflammation and the tissue-resident innate immune cells, the microglia, respond and
contribute to neurodegenerative pathology. Although microglia have been the focus of work …
contribute to neurodegenerative pathology. Although microglia have been the focus of work …
[HTML][HTML] Links between COVID-19 and Parkinson's disease/Alzheimer's disease: reciprocal impacts, medical care strategies and underlying mechanisms
P Huang, LY Zhang, YY Tan, SD Chen - Translational Neurodegeneration, 2023 - Springer
The impact of coronavirus disease 2019 (COVID-19) pandemic on patients with
neurodegenerative diseases and the specific neurological manifestations of COVID-19 have …
neurodegenerative diseases and the specific neurological manifestations of COVID-19 have …
Focused ultrasound–mediated blood-brain barrier opening in Alzheimer's disease: long-term safety, imaging, and cognitive outcomes
OBJECTIVE MRI-guided low-intensity focused ultrasound (FUS) has been shown to
reversibly open the blood-brain barrier (BBB), with the potential to deliver therapeutic agents …
reversibly open the blood-brain barrier (BBB), with the potential to deliver therapeutic agents …
[HTML][HTML] Transcriptomic profiling identifies CD8+ T cells in the brain of aged and alzheimer's disease transgenic mice as tissue-resident memory T cells
B Altendorfer, MS Unger, R Poupardin… - The Journal of …, 2022 - journals.aai.org
Peripheral immune cell infiltration into the brain is a prominent feature in aging and various
neurodegenerative diseases such as Alzheimer's disease (AD). As AD progresses, CD8+ T …
neurodegenerative diseases such as Alzheimer's disease (AD). As AD progresses, CD8+ T …