Life cycle stages, specific organelles and invasion mechanisms of Eimeria species

A Burrell, FM Tomley, S Vaughan… - Parasitology, 2020 - cambridge.org
Apicomplexans, including species of Eimeria, pose a real threat to the health and wellbeing
of animals and humans. Eimeria parasites do not infect humans but cause an important …

[HTML][HTML] B-cell epitope mapping for the design of vaccines and effective diagnostics

TA Ahmad, AE Eweida, SA Sheweita - Trials in Vaccinology, 2016 - Elsevier
The increasing resistance of many microbial strains to antibiotics, delayed laboratory results,
and side effects of many chemotherapeutics has raised the need to search for sensitive …

[HTML][HTML] Recombinant anticoccidial vaccines-a cup half full?

DP Blake, I Pastor-Fernández, MJ Nolan… - Infection, Genetics and …, 2017 - Elsevier
Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The
occurrence of coccidiosis is currently controlled through a combination of good husbandry …

[HTML][HTML] Development of immunization trials against Eimeria spp.

TA Ahmad, BA El-Sayed, LH El-Sayed - Trials in Vaccinology, 2016 - Elsevier
Coccidiosis is a major intestinal disease affecting economically valuable livestock animals
such as chickens and turkeys. Economic losses are associated with decreased productivity …

[HTML][HTML] Protective efficacy of multiepitope vaccines constructed from common antigens of Eimeria species in chickens

C Chen, J Su, M Lu, L Xu, R Yan, X Li, X Song - Veterinary Research, 2023 - Springer
Clinical avian coccidiosis is typically caused by coinfection with several Eimeria species.
Recombinant protein and DNA vaccines have shown promise in controlling coccidiosis. On …

[HTML][HTML] Designing multiepitope-based vaccine against Eimeria from immune mapped protein 1 (IMP-1) antigen using immunoinformatic approach

T Madlala, VT Adeleke, AJ Fatoba, M Okpeku… - Scientific Reports, 2021 - nature.com
Drug resistance against coccidiosis has posed a significant threat to chicken welfare and
productivity worldwide, putting daunting pressure on the poultry industry to reduce the use of …

[HTML][HTML] A multiepitope vaccine encoding four Eimeria epitopes with PLGA nanospheres: a novel vaccine candidate against coccidiosis in laying chickens

ZQ Yu, SY Chen, JM Huang, WX Ding, YF Chen… - Veterinary …, 2022 - Springer
With a worldwide distribution, Eimeria spp. could result in serious economic losses to the
poultry industry. Due to drug resistance and residues, there are no ideal drugs and vaccines …

[HTML][HTML] Eimeria falciformis secretes extracellular vesicles to modulate proinflammatory response during interaction with mouse intestinal epithelial cells

JS Olajide, L Xiong, S Yang, Z Qu, X Xu, B Yang… - Parasites & …, 2022 - Springer
Background Protozoan parasite secretions can be triggered by various modified media and
diverse physicochemical stressors. Equally, host-parasite interactions are known to co-opt …

[HTML][HTML] An Eimeria maxima Antigen: Its Functions on Stimulating Th1 Cytokines and Protective Efficacy Against Coccidiosis

C Chen, Y Zhang, J Liu, M Wang, M Lu, L Xu… - Frontiers in …, 2022 - frontiersin.org
A consensus is that the Th1 immune response plays a predominant role against avian
coccidiosis. Therefore, an antigen with the ability to induce Th1 cytokine responses is an …

T-cell epitope mapping for the design of powerful vaccines

TA Ahmad, AE Eweida, LH El-Sayed - Vaccine Reports, 2016 - Elsevier
Epitope mapping has emerged as a powerful tool to design vaccines. It proved itself a
number of times to reveal the building blocks of potent immuno-prophylactics. T-cell epitope …