Simvastatin-Encapsulated Topical Liposomal Gel for Augmented Wound Healing: Optimization Using the Box-Behnken Model, Evaluations, and In Vivo Studies

M Rahamathulla, R Pokale, Y Al-ebini, RAM Osmani… - Pharmaceuticals, 2024 - mdpi.com
Statins function beyond regulating cholesterol and, when administered systemically, can
promote wound healing. However, studies have yet to explore the topical use of statins for …

Enhanced behavioral impact of optimized bupropion-encapsulated bilosomes over traditional niosomes treating depression

K Harini, K Girigoswami, M Vajagathali, D Bose… - Naunyn-Schmiedeberg's …, 2024 - Springer
Abstract Bupropion (Bpn), an FDA-approved NDRI (norepinephrine-dopamine reuptake
inhibitor), poses risks of seizures and liver failure due to its stimulant properties …

Size-dependent effects of niosomes on the penetration of methotrexate in skin layers

S Soni, K Baghel, ML Soni, SK Kashaw… - Future Journal of …, 2024 - Springer
Background Niosomes hold promise as drug delivery systems for cancer treatment, with
niosome size impacting stability, biodistribution, and effectiveness. This study optimized …

The Exploitation of Sodium Deoxycholate-Stabilized Nano-Vesicular Gel for Ameliorating the Antipsychotic Efficiency of Sulpiride

MH Abdallah, MM Shahien, A Alshammari, S Ibrahim… - Gels, 2024 - mdpi.com
The present study explored the effectiveness of bile-salt-based nano-vesicular carriers
(bilosomes) for delivering anti-psychotic medication, Sulpiride (Su), via the skin. A response …

Advancement of all-trans retinoic acid delivery systems in dermatological application

SSS Omar, H Hadi - Cosmetics, 2022 - mdpi.com
Dermatological conditions, such as acne, photoaging, psoriasis, and wounds, have been
treated topically with all-trans retinoic acid (ATRA) for many years owing to its anti …

[PDF][PDF] Development and evaluation of curcumin-loaded vesicular carriers: impact of formulation variables

D Momekova, V Gugleva, P Petrov - Pharmacia, 2024 - pharmacia.pensoft.net
Vesicular carriers are a well-established approach to improving the technological and
biopharmaceutical characteristics of the loaded cargo. The current manuscript is focused on …

[PDF][PDF] Design and optimization of fluconazole-loaded pharmacosome gel for enhancing transdermal permeation and treating fungal infections through box-behnken …

S Naveentaj, YI Muzib, R Radha - Int J App Pharm, 2023 - academia.edu
DESIGN AND OPTIMIZATION OF FLUCONAZOLE-LOADED PHARMACOSOME GEL FOR
ENHANCING TRANSDERMAL PERMEATION AND TREATING FUNGAL INFECTIO Page 1 …

Liposomes and Other Nanocarriers for the Treatment of Acne Vulgaris: Improved Therapeutic Efficacy and Skin Tolerability

N Dragicevic, HI Maibach - Pharmaceutics, 2024 - mdpi.com
Acne vulgaris is a common dermatologic disorder that affects approximately 85% of
teenagers, which significantly impacts the quality of life in adolescents. It is a chronic …

Lipid-based nanoparticles as a promising treatment for the skin cancer

P Golestani - Heliyon, 2024 - cell.com
The prevalence of skin disorders, especially cancer, is increasing worldwide. Several factors
are involved in causing skin cancer, but ultraviolet (UV) light, including sunlight and tanning …

Overcoming Skin Barrier with Transfersomes: Opportunities, Challenges, and Applications

B Dixena, R Madhariya, A Panday, A Ram… - Current Drug …, 2024 - ingentaconnect.com
Background: Transdermal drug delivery systems (TDDS) offer several advantages over
traditional methods like injections and oral administration, including preventing first-pass …