Can BCG vaccine protect against COVID‐19 via trained immunity and tolerogenesis?

P Basak, N Sachdeva, D Dayal - Bioessays, 2021 - Wiley Online Library
As the number of infections and mortalities from the SARS‐CoV‐2 pandemic continues to
rise, the development of an effective therapy against COVID‐19 becomes ever more urgent …

[PDF][PDF] Vasculitis in COVID-19: a literature review

SA Almashat - J vasc, 2020 - researchgate.net
Vasculitis has been linked to COVID-19 as a suspected pathological pattern in different
cases, however, it is not yet considered a major pathology. This virus has different clinical …

Working hypothesis for glucose metabolism and SARS-CoV-2 replication: interplay between the hexosamine pathway and interferon RF5 triggering …

HA Laviada-Molina, I Leal-Berumen… - Frontiers in …, 2020 - frontiersin.org
Respiratory epithelial cells, dendritic cells (DCs) and macrophages (1) secrete low levels of
the antiviral factor interferons (IFNs)(2) and high levels of proinflammatory cytokines such as …

Bacillus Calmette–Guérin in Immuno-Regulation of Alzheimer's Disease

BY Klein, CL Greenblatt, ON Gofrit… - Frontiers in Aging …, 2022 - frontiersin.org
Bacillus Calmette–Guérin is frequently the treatment of choice of superficial bladder cancer.
Exposing the urinary bladder of elderly patients with bladder cancer to the BCG vaccine …

Role of immune cells in diabetic kidney disease

X Yang, S Mou - Current Gene Therapy, 2017 - ingentaconnect.com
Diabetic Kidney Disease (DKD) is one of the major complications of Diabetes Mellitus (DM)
and is currently the most common cause of End-Stage Renal Disease (ESRD) worldwide …

The association between BCG treatment in patients with bladder cancer and subsequent risk of developing Alzheimer and other dementia.—A Swedish nationwide …

E Wang, O Hagberg, PU Malmström - PLoS One, 2023 - journals.plos.org
Background Alzheimer's disease (AD) affects 50 million people worldwide. The immune
system plays a major role in the pathogenesis of AD. Several retrospective analyses have …

Neonatal vaccination with bacillus Calmette–Guérin and hepatitis B vaccines modulates hippocampal synaptic plasticity in rats

Q Li, F Qi, J Yang, L Zhang, H Gu, J Zou, Q Yuan… - Journal of …, 2015 - Elsevier
Immune activation can exert multiple effects on synaptic transmission. Our study
demonstrates the influence of neonatal vaccination on hippocampal synaptic plasticity in …

Research progress in the off-target effects of Bacille Calmette–Guérin vaccine

Y Wu, X Zhang, L Zhou, J Lu, F Zhu… - Chinese Medical …, 2023 - journals.lww.com
Abstract Bacille Calmette–Guérin (BCG) vaccine is designed to provide protection against
tuberculosis (TB). However, numerous epidemiological, clinical, and immunological studies …

Immunization with an adenovirus-vectored TB vaccine containing Ag85A-Mtb32 effectively alleviates allergic asthma

Y Zhang, Y Feng, L Li, X Ye, J Wang, Q Wang… - Journal of molecular …, 2018 - Springer
Current treatments for allergic asthma primarily ameliorate symptoms rather than inhibit
disease progression. Regulating the excessive T helper type 2 (Th2) responses may prevent …

Neonatal Bacillus Calmette-Guérin vaccination alleviates lipopolysaccharide-induced neurobehavioral impairments and neuroinflammation in adult mice

J Yang, F Qi, Z Yao - Molecular Medicine Reports, 2016 - spandidos-publications.com
Abstract The Bacillus Calmette-Guérin (BCG) vaccine is routinely administered to human
neonates worldwide. BCG has recently been identified as a neuroprotective immune …