Sarcopenia, a geriatric syndrome that is characterized by a progressive and generalized
skeletal muscle disorder, can be associated with many comorbidities, including obesity …

The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Background Elderly people with low lean and high fat mass, are diagnosed with sarcopenic
obesity (SO), and often have poor clinical outcomes. This study aimed to explore the …

Frailty is a common geriatric syndrome characterized by increased vulnerability and is
associated with adverse clinical events such as falls, hospitalization, and death. Early …

With global population aging, age-related diseases, especially sarcopenia, have attracted
much attention in recent years. Characterized by low muscle strength, low muscle quantity or …

Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …

The prolonged immobilization associated with COVID-19 infection and the restrictions
imposed by the pandemic have determined major changes in physical activity and eating …

Frailty and sarcopenia are age-related diseases, and exhibit a concomitant relationship, as
they share many common clinical features and etiological factors. Transitions within frailty …

Obesity and type 2 diabetes account for a considerable proportion of the global burden of
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …

Multisystem derangements encompassing musculoskeletal, stress, and metabolic response
have been described in older adults with physical frailty and sarcopenia (PF&S). Whether …