Crosstalk Between Autophagy and Inflammation in Chronic Cerebral Ischaemia

H Zhou, L Zhang, X Li, Z Huang - Cellular and Molecular Neurobiology, 2023 - Springer
Chronic cerebral ischaemia (CCI) is a high-incidence cardiovascular and cerebrovascular
disease that is very common in clinical practice. Although many pathogenic mechanisms …

The potential mechanism and clinical application value of remote ischemic conditioning in stroke

Y Zhu, X Li, X Lei, L Tang, D Wen, B Zeng… - Neural Regeneration …, 2025 - journals.lww.com
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning
against stroke. Although numerous animal researches have shown that the neuroprotective …

[HTML][HTML] Pericyte Dysfunction Contributes to Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats

S Lin, B Landon, H Zhang, K Jin - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Vascular cognitive impairment (VCI) encompasses cognitive disorders associated with
cerebrovascular disease, often manifesting as white matter lesions (WMLs), irrespective of …

VEGF loaded nanofiber membranes inhibit chronic cerebral hypoperfusion-induced cognitive dysfunction by promoting HIF-1a/VEGF mediated angiogenesis

YF Wu, KY Jin, DP Wang, Q Lin, J Sun, SH Su… - … , Biology and Medicine, 2023 - Elsevier
We investigated the potential effects and mechanisms of vascular endothelial growth factor
(VEGF)-nanofiber membranes (NFMs) treatment in a rat model of chronic cerebral …

Costunolide covalently targets and inhibits CaMKII phosphorylation to reduce ischemia-associated brain damage

W Liu, W Yang, R Niu, L Cong, M Jiang, G Bai - Phytomedicine, 2023 - Elsevier
Background Chronic cerebral hypoperfusion (CCH) is a leading cause of disability and
mortality worldwide. Restoring cerebral blood flow (CBF) through vasodilatation is …

Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion

YF Wu, J Sun, M Chen, Q Lin, KY Jin, SH Su… - International …, 2023 - Elsevier
Currently, there are no effective therapeutic targets for the treatment of chronic cerebral
hypoperfusion (CCH)-induced cerebral ischemic injury. Vascular endothelial growth factor …

[HTML][HTML] Elucidating the mechanisms of Buyang Huanwu Decoction in treating chronic cerebral ischemia: A combined approach using network pharmacology …

Y Cao, W Yao, T Yang, M Yang, Z Liu, H Luo, Z Cao… - Phytomedicine, 2024 - Elsevier
Objective This study aimed to explore the potential mechanisms of Buyang Huanwu
Decoction (BHD) in regulating the AKT/TP53 pathway and reducing inflammatory responses …

[PDF][PDF] 激光散斑衬比成像技术在慢性脑缺血动物模型中的应用研究进展

唐鑫, 谭洁 - 中国比较医学杂志, 2024 - zgbjyx.cnjournals.com
激光散斑衬比成像技术采用可视化, 可量化的方法实时动态测量组织或器官的微循环血流量.
因其活体检测, 实时成像及操作简单等优点, 已在微循环检测的多个领域中应用 …

Scalp mechanical stimulation alleviates cerebral hypoperfusion in rats with 2-VO by controlling cerebral edema

Y Tan, H Zhang, C Zhang, W Chen, T Peng… - Journal of Traditional …, 2023 - Elsevier
Objective To illustrate the cerebral protective effect of scalp mechanical stimulation (SMS),
similar to scalp acupuncture in basic mechanism, on cerebral edema in rats with cerebral …