GABAergic and glutamatergic cells in the inferior colliculus dynamically express the GABAAR γ1 subunit during aging
LC Robinson, O Barat, JG Mellott - Neurobiology of aging, 2019 - Elsevier
Age-related hearing loss may result, in part, from declining levels of γ-amino butyric acid
(GABA) in the aging inferior colliculus (IC). An upregulation of the GABA AR γ 1 subunit …
(GABA) in the aging inferior colliculus (IC). An upregulation of the GABA AR γ 1 subunit …
Inferior collicular cells that project to the auditory thalamus are increasingly surrounded by perineuronal nets with age
The age-related loss of GABA in the inferior colliculus (IC) likely plays a role in the
development of age-related hearing loss. Perineuronal nets (PNs), specialized aggregates …
development of age-related hearing loss. Perineuronal nets (PNs), specialized aggregates …
Nicotine reduces age-related changes in cortical neural oscillations without affecting auditory brainstem responses
JA Rumschlag, JW Lovelace, J Kokash, A Hussain… - Neurobiology of …, 2022 - Elsevier
Neural oscillations at specific frequency bands are associated with cognitive functions and
can identify abnormalities in cortical dynamics. In this study, we analyzed EEG signals …
can identify abnormalities in cortical dynamics. In this study, we analyzed EEG signals …
Hybrid auditory fMRI: In pursuit of increasing data acquisition while decreasing the impact of scanner noise
Background Two challenges in auditory fMRI include the loud scanner noise during sound
presentation and slow data acquisition. Here, we introduce a new auditory imaging protocol …
presentation and slow data acquisition. Here, we introduce a new auditory imaging protocol …
The Speech Envelope Following Response in Normal and Hearing Impaired Listeners
T Wartenberg, M Garrett, S Verhulst - BioRxiv, 2022 - biorxiv.org
The aim of this work was to investigate the perceptual relevance of the frequency following
response to the syllable/da/for speech intelligibility in noise based on age and hearing …
response to the syllable/da/for speech intelligibility in noise based on age and hearing …
[HTML][HTML] Model-predicted balance between neural excitation and inhibition was maintained despite of age-related decline in sensory evoked local field potential in rat …
S Kang, Y Hayashi, M Bruyns-Haylett… - Frontiers in Systems …, 2020 - frontiersin.org
The balance between neural excitation and inhibition has been shown to be crucial for
normal brain function. However, it is unclear whether this balance is maintained through …
normal brain function. However, it is unclear whether this balance is maintained through …
Changes in Cortical Directional Connectivity during Difficult Listening in Younger and Older Adults
One way to investigate the mechanisms that underlie speech comprehension under difficult
listening conditions is via cortical connectivity. The innovative Network Localized Granger …
listening conditions is via cortical connectivity. The innovative Network Localized Granger …
Neural signatures of disordered multi-talker speech perception in adults with normal hearing
A Parthasarathy, KE Hancock, K Bennett, V DeGruttola… - bioRxiv, 2019 - biorxiv.org
In social settings, speech waveforms from nearby speakers mix together in our ear canals.
The brain unmixes the attended speech stream from the chorus of background speakers …
The brain unmixes the attended speech stream from the chorus of background speakers …
Contributions of low-and high-frequency sensorineural hearing deficits to speech intelligibility in noise
S Verhulst, A Warzybok - BioRxiv, 2018 - biorxiv.org
This study investigates the role of hearing sensitivity, age and supra-threshold hearing to
speech recognition in quiet, stationary, and modulated noise. Three participant groups were …
speech recognition in quiet, stationary, and modulated noise. Three participant groups were …
[HTML][HTML] Sensory representations and pupil-indexed listening effort provide complementary contributions to multi-talker speech intelligibility
Optimal speech perception in noise requires successful separation of the target speech
stream from multiple competing background speech streams. The ability to segregate these …
stream from multiple competing background speech streams. The ability to segregate these …