Significance of hyperreflective foci as an optical coherence tomography biomarker in retinal diseases: characterization and clinical implications
S Fragiotta, S Abdolrahimzadeh… - Journal of …, 2021 - Wiley Online Library
Hyperreflective foci (HRF) is a term coined to depict hyperreflective dots or roundish lesions
within retinal layers visualized through optical coherence tomography (OCT) …
within retinal layers visualized through optical coherence tomography (OCT) …
[HTML][HTML] Quantitative approaches in multimodal fundus imaging: state of the art and future perspectives
A Arrigo, E Aragona, MB Parodi, F Bandello - Progress in Retinal and Eye …, 2023 - Elsevier
When it first appeared, multimodal fundus imaging revolutionized the diagnostic workup and
provided extremely useful new insights into the pathogenesis of fundus diseases. The recent …
provided extremely useful new insights into the pathogenesis of fundus diseases. The recent …
[HTML][HTML] The effect of pegcetacoplan treatment on photoreceptor maintenance in geographic atrophy monitored by artificial intelligence–based OCT analysis
Purpose To investigate the therapeutic effect of intravitreal pegcetacoplan on the inhibition
of photoreceptor (PR) loss and thinning in geographic atrophy (GA) on conventional spectral …
of photoreceptor (PR) loss and thinning in geographic atrophy (GA) on conventional spectral …
[HTML][HTML] Predicting topographic disease progression and treatment response of pegcetacoplan in geographic atrophy quantified by deep learning
Purpose To identify disease activity and effects of intravitreal pegcetacoplan treatment on
the topographic progression of geographic atrophy (GA) secondary to age-related macular …
the topographic progression of geographic atrophy (GA) secondary to age-related macular …
Clinical validation for automated geographic atrophy monitoring on OCT under complement inhibitory treatment
Geographic atrophy (GA) represents a late stage of age-related macular degeneration,
which leads to irreversible vision loss. With the first successful therapeutic approach, namely …
which leads to irreversible vision loss. With the first successful therapeutic approach, namely …
Melanophages give rise to hyperreflective foci in AMD, a disease-progression marker
S Augustin, M Lam, S Lavalette, A Verschueren… - Journal of …, 2023 - Springer
Retinal melanosome/melanolipofuscin-containing cells (MCCs), clinically visible as
hyperreflective foci (HRF) and a highly predictive imaging biomarker for the progression of …
hyperreflective foci (HRF) and a highly predictive imaging biomarker for the progression of …
Automated quantitative assessment of retinal fluid volumes as important biomarkers in neovascular age-related macular degeneration
Purpose To evaluate retinal fluid volume data extracted from optical coherence tomography
(OCT) scans by artificial intelligence algorithms in the treatment of neovascular age-related …
(OCT) scans by artificial intelligence algorithms in the treatment of neovascular age-related …
[HTML][HTML] Disease activity and therapeutic response to pegcetacoplan for geographic atrophy identified by deep learning-based analysis of OCT
Purpose To quantify morphological changes of the photoreceptors (PRs) and retinal pigment
epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using …
epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using …
Artificial intelligence in retinal imaging: current status and future prospects
KA Heger, SM Waldstein - Expert review of medical devices, 2024 - Taylor & Francis
Introduction The steadily growing and aging world population, in conjunction with
continuously increasing prevalences of vision-threatening retinal diseases, is placing an …
continuously increasing prevalences of vision-threatening retinal diseases, is placing an …
Imaging and artificial intelligence for progression of age-related macular degeneration
Age-related macular degeneration (AMD) is a leading cause of severe vision loss. With our
aging population, it may affect 288 million people globally by the year 2040. AMD …
aging population, it may affect 288 million people globally by the year 2040. AMD …