Pharmacotherapy of Alzheimer's disease: an overview of systematic reviews

R Majidazar, E Rezazadeh-Gavgani… - European journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease and the most
common cause of dementia. In this umbrella systematic review (SR), we summarized the …

Modulation of neurotrophic factors in the treatment of dementia, stroke and TBI: Effects of Cerebrolysin

K Rejdak, H Sienkiewicz‐Jarosz… - Medicinal Research …, 2023 - Wiley Online Library
Neurotrophic factors (NTFs) are involved in the pathophysiology of neurological disorders
such as dementia, stroke and traumatic brain injury (TBI), and constitute molecular targets of …

Cerebrolysin for stroke, neurodegeneration, and traumatic brain injury: review of the literature and outcomes

B Fiani, C Covarrubias, A Wong, T Doan… - Neurological …, 2021 - Springer
Cerebrolysin therapy has the potential to significantly aid in the treatment of a wide variety of
debilitating neurological diseases including ischemic strokes, neurodegenerative disorders …

[HTML][HTML] Neurotrophins in the neuropathophysiology, course, and complications of obstructive sleep apnea—a narrative review

A Gabryelska, S Turkiewicz, M Ditmer… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea (OSA) is a disorder characterized by chronic intermittent hypoxia
and sleep fragmentation due to recurring airway collapse during sleep. It is highly prevalent …

[HTML][HTML] Therapeutic approaches for improving cognitive function in the aging brain

L Chen, J Jiao, Y Zhang - Frontiers in Neuroscience, 2022 - frontiersin.org
The rapid aging of populations around the world has become an unprecedented challenge.
Aging is associated with cognitive impairment, including dementia and mild cognitive …

[HTML][HTML] Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway

Q Huang, C Zhang, S Dong, J Han, S Qu, T Xie… - Chinese Medicine, 2022 - Springer
Abstract Background Alzheimer's Disease (AD) is a serious neurodegenerative disease and
there is currently no effective treatment for AD progression. The use of TCM as a potential …

[HTML][HTML] Chinese herbal extracts exert neuroprotective effect in Alzheimer's disease mouse through the dopaminergic synapse/apoptosis signaling pathway

Q Huang, C Zhang, S Qu, S Dong, Q Ma… - Frontiers in …, 2022 - frontiersin.org
Background: Alzheimer's disease (AD) as an age-related, irreversible neurodegenerative
disease, characterized by cognitive dysfunction, has become progressively serious with a …

[HTML][HTML] Ellagic acid modulates the amyloid precursor protein gene via superoxide dismutase regulation in the entorhinal cortex in an experimental alzheimer's model

WS Ramadan, S Alkarim - Cells, 2021 - mdpi.com
Patients suffering from Alzheimer's disease (AD) are still increasing worldwide. The
development of (AD) is related to oxidative stress and genetic factors. This study …

[HTML][HTML] Asparagopsis Genus: What We Really Know About Its Biological Activities and Chemical Composition

JMS Ponte, AML Seca, MC Barreto - Molecules, 2022 - mdpi.com
Although the genus Asparagopsis includes only two taxonomically accepted species, the
published literature is unanimous about the invasive nature of this genus in different regions …

[HTML][HTML] Pentoxifylline as add-on treatment to donepezil in copper sulphate-induced Alzheimer's disease-like neurodegeneration in rats

MM Elseweidy, M Mahrous, SI Ali, MA Shaheen… - Neurotoxicity …, 2023 - Springer
Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is
characterized by behavioral, cognitive, and progressive memory impairments. Extensive …