Metabolic syndrome pathophysiology and predisposing factors

A Bovolini, J Garcia, MA Andrade… - International journal of …, 2021 - thieme-connect.com
Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors with high prevalence
among adult populations and elevated costs for public health systems worldwide. Despite …

The association of periodontal diseases with metabolic syndrome and obesity

S Jepsen, J Suvan, J Deschner - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a multifactorial chronic inflammatory disease associated with dysbiotic
plaque biofilms and characterized by progressive destruction of the tooth‐supporting …

Mechanisms of dysfunction in the aging vasculature and role in age-related disease

AJ Donato, DR Machin, LA Lesniewski - Circulation research, 2018 - Am Heart Assoc
Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the
United States and many developed nations. Two major age-related arterial phenotypes …

Analysis of association between vitamin D deficiency and insulin resistance

I Szymczak-Pajor, A Śliwińska - Nutrients, 2019 - mdpi.com
Recent evidence revealed extra skeleton activity of vitamin D, including prevention from
cardiometabolic diseases and cancer development as well as anti-inflammatory properties …

Oxidative stress in obesity: a critical component in human diseases

L Marseglia, S Manti, G D'Angelo, A Nicotera… - International journal of …, 2014 - mdpi.com
Obesity, a social problem worldwide, is characterized by an increase in body weight that
results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and …

Mitochondrial dysfunction in obesity

AH de Mello, AB Costa, JDG Engel, GT Rezin - Life sciences, 2018 - Elsevier
Obesity leads to various changes in the body. Among them, the existing inflammatory
process may lead to an increase in the production of reactive oxygen species (ROS) and …

The molecular mechanisms by which vitamin D prevents insulin resistance and associated disorders

I Szymczak-Pajor, J Drzewoski, A Śliwińska - International journal of …, 2020 - mdpi.com
Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …

The action of vitamin D in adipose tissue: is there the link between vitamin D deficiency and adipose tissue-related metabolic disorders?

I Szymczak-Pajor, K Miazek, A Selmi… - International Journal of …, 2022 - mdpi.com
Adipose tissue plays an important role in systemic metabolism via the secretion of
adipocytokines and storing and releasing energy. In obesity, adipose tissue becomes …

The role of adipose tissue immune cells in obesity and low-grade inflammation

M Mraz, M Haluzik - Journal of Endocrinology, 2014 - joe.bioscientifica.com
Adipose tissue (AT) lies at the crossroad of nutrition, metabolism, and immunity; AT
inflammation was proposed as a central mechanism connecting obesity with its metabolic …

Inflammatory cytokines in general and central obesity and modulating effects of physical activity

FM Schmidt, J Weschenfelder, C Sander, J Minkwitz… - PloS one, 2015 - journals.plos.org
Context Chronic systemic inflammation in obesity originates from local immune responses in
visceral adipose tissue. However, assessment of a broad range of inflammation-mediating …