Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are
significant in development and reproduction of organisms. Recently, emerging evidences …

Background Lung cancer is the most common and deadliest cancer worldwide, and
approximately 90% of all lung cancer deaths are caused by tumor metastasis. Tumor …

The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …

Introduction lncRNAs are major players in regulatory networks orchestrating multiple cellular
functions, such as 3D chromosomal interactions, epigenetic modifications, gene expression …

Abstract DNMT1 (DNA methyltransferase 1) is the predominant member of the DNMT family
and the most abundant DNMT in various cell types. It functions as a maintenance DNMT and …

DNA methylation is one of the main epigenetic mechanisms in cancer development and
progression. Aberrant DNA methylation of CpG islands within promoter regions contributes …

This comprehensive review elucidates the intricate roles of long non-coding RNAs
(lncRNAs) within the colorectal cancer (CRC) microenvironment, intersecting the domains of …

Breast cancer, as a highly heterogeneous malignant tumor, is one of the primary causes of
death among females worldwide. The etiology of breast cancer involves aberrant epigenetic …

Cancer is a comprehensive classification encompassing more than 100 forms of
malignancies that manifest in diverse tissues within the human body. Recent studies have …