ABSTRACT The North American Great Lakes are a vital natural resource that provide fish
and wildlife habitat, as well as drinking water and waste assimilation services for millions of …

The binding affinity of bisphenol A (BPA) to estrogen receptors (ERs) is much lower than that
of 17β-estradiol (E 2), and whether there are other molecular mechanisms responsible for …

Despite a wide number of toxicological studies that describe benzo [a] pyrene (BaP) effects,
the metabolic mechanisms that underlie these effects in fish are largely unknown. Of great …

Abstract Benzo [a] pyrene (BaP), a widely existed polycyclic aromatic hydrocarbon pollutant
in aquatic environment, has toxic effects on marine animals and their generations, but the …

Phenanthrene (PHE) is a common polycyclic aromatic hydrocarbon (PAH) in aquatic
environments, and this contaminant can cause adverse effects on teleostean performance …

Chemical induced changes in fish biomarkers vitellogenin (VTG), secondary sex
characteristics (SSC), and sex ratio indicate modes/mechanisms of action (MOAs) of EAS …

Abstract Benzo [a] pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that has been
implicated in modulating aromatase enzyme function with the potential to interrupt normal …

As zebrafish larvae are being increasingly applied to toxicity testing, there is a need to
understand the potential for xenobiotic metabolism by these early life-stage organisms. The …

Publisher Summary Zebrafish are being used as a model in all areas of environmental
toxicology, for example to discern mechanisms, as a tool in testing, in monitoring the toxic …

Benzo [a] pyrene (BaP) is a common environmental disrupting chemical that can cause
endocrine disorders in organisms. However, the continued interference effects of BaP on …