Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …

Antibiotic resistance has become an indispensably alarming menace to the global
community. The primary factors are overuse and abuse of antibiotics, lack of novel …

Background Global prescription drug use has been increasing continuously for decades.
The gut microbiome, a key contributor to health status, can be altered by prescription drug …

Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases
(LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we …

abstract Bloodstream infections (BSI) are among the most frequent complications in
neutropenic cancer patients and, if caused by Gram-negative rods, are associated with high …

A prospective cohort study was conducted in nine hematology wards at tertiary care centres
or at university hospitals located throughout Italy from January 2009 to December 2012. All …

The aim of this study was to identify risk factors for mortality in patients suffering from
hematological malignancies (HMs) with bloodstream infections (BSIs) caused by Klebsiella …

Background Patients with haematological malignancies have higher risk of acquiring
bloodstream infection (BSI). Neutropenia resulting from cytotoxic chemotherapy is the most …

Little information is currently available regarding bloodstream infection (BSI) in patients with
solid tumors who, for a variety of reasons, are particularly predisposed to develop this …

Host defense from infection depends upon a complex, integrated system of physical barriers
(eg, skin, stomach acid, and mucociliary clearance), innate immunity (eg, phagocytic cells …