Cardiovascular disease (CVD) is the number one threat that seriously endangers human
health. However, the mechanism of their occurrence is not completely clear. Increasing …

A variety of complex risk factors and pathological mechanisms contribute to myocardial
stress, which ultimately promotes the development of cardiovascular diseases, including …

Mitochondria, the most crucial energy-generating organelles in eukaryotic cells, play a
pivotal role in regulating energy metabolism. However, their significance extends beyond …

The skin, serving as the body's primary defense against external elements, plays a crucial
role in protecting the body from infections and injuries, as well as maintaining overall …

Accumulating evidence highlights the key importance of innate immunity in heart
hypertrophy and failure. Though stimulator of interferon genes (STING) is an integral innate …

Sigmar1 is a ubiquitously expressed, multifunctional protein known for its cardioprotective
roles in cardiovascular diseases. While accumulating evidence indicate a critical role of …

Background: Aging patients easily suffer from non-ST segment elevation myocardial
infarction (NSTEMI). Our previous studies revealed declined function of endothelial …

Vascular smooth muscle cell (VSMC) senescence promotes atherosclerosis via lipid-
mediated mitochondrial dysfunction and oxidative stress. However, the mechanisms of …

Ethnopharmacological relevance Hyperlipidemia as a major health issue has attracted
much public attention. As a geographical indication product of China, Liupao tea (LPT) is a …

Increasing evidence demonstrates that aging influences the brain's response to traumatic
brain injury (TBI), setting the stage for neurodegenerative pathology like Alzheimer's disease …