Cholestatic liver diseases are caused by a range of hepatobiliary insults and involve
complex interactions among environmental and genetic factors. Little is known about the …

Background Gallstone disease (GD) belongs to the most frequent disorders in
gastroenterology and causes high costs in our health‐care systems. Gallstones are …

Background Gallstone disease (GSD) is a common and costly biliary disorder. Multiple
studies have investigated the associations between blood lipid metabolism and GSD risk; …

This review integrates historical biochemical and modern genetic findings that underpin our
understanding of the low-density lipoprotein (LDL) dyslipidemias that bear on human …

The presence of gallstone disease (GSD) was reported to be positively associated with
diabetes risk. Whether the association is causal remains unclear. We aim to examine the …

Gallstone disease affects almost 20% of individuals in Westernized countries. As its
incidence in the developing countries is rising considerably, currently, it is the second most …

Gallstone disease (GSD) is one of the most common biliary tract disorders worldwide. The
prevalence, however, varies from 5.9–21.9% in Western society to 3.1–10.7% in Asia. Most …

Background Gallstone disease is associated with p. D19H of ABCG8 as well as alterations
of cholesterol and bile acid metabolism. However, molecular mechanisms have not been …

Background Gallstones are abnormal masses caused by impaired metabolism of
cholesterol, bilirubin, or bile salts in the gallbladder or biliary tract. ATP-binding cassette …

The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all
vertebrates. Some of these transporters play a key role in xenobiotic defense and are …