Serotonergic regulation of prefrontal cortical circuitries involved in cognitive processing: a review of individual 5-HT receptor mechanisms and concerted effects of 5 …
SC Leiser, Y Li, AL Pehrson, E Dale… - ACS chemical …, 2015 - ACS Publications
It has been known for several decades that serotonergic neurotransmission is a key
regulator of cognitive function, mood, and sleep. Yet with the relatively recent discoveries of …
regulator of cognitive function, mood, and sleep. Yet with the relatively recent discoveries of …
Distribution of serotonin receptor 5-HT6 mRNA in rat neuronal subpopulations: a double in situ hybridization study
L Helboe, J Egebjerg, IEM De Jong - Neuroscience, 2015 - Elsevier
Abstract The 5-HT 6 receptor (5-HT 6 R) is almost exclusively expressed in the brain and
has emerged as a promising target for cognitive disorders, including Alzheimer's disease. In …
has emerged as a promising target for cognitive disorders, including Alzheimer's disease. In …
5-HT6 receptor agonism facilitates emotional learning
M Pereira, BJ Martynhak, R Andreatini… - Frontiers in …, 2015 - frontiersin.org
Serotonin (5-HT) and its receptors play crucial roles in various aspects of mood and
cognitive functions. However, the role of specific 5-HT receptors in these processes remains …
cognitive functions. However, the role of specific 5-HT receptors in these processes remains …
Serotonin6 receptors in the dorsal hippocampus regulate depressive-like behaviors in unilateral 6-hydroxydopamine-lesioned Parkinson's rats
KC Liu, JY Li, HH Tan, CX Du, W Xie, YM Zhang… - …, 2015 - Elsevier
Preclinical studies indicate both activation and blockade of serotonin 6 (5-HT 6) receptors
may produce antidepressant-like effects. Depression is a common symptom in Parkinson's …
may produce antidepressant-like effects. Depression is a common symptom in Parkinson's …
Distribution of 5-HT receptors in the central nervous system: an update
Almost 10 years have passed since we wrote the review on the “Distribution of 5-HT
receptors in the central nervous system” in this series (Mengod, Cortés, Vilaró, & Hoyer …
receptors in the central nervous system” in this series (Mengod, Cortés, Vilaró, & Hoyer …
Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo
JT Brouard, JV Schweimer, R Houlton… - ACS Chemical …, 2015 - ACS Publications
5-Hydroxytryptamine (5-HT) neurons in the midbrain dorsal raphe nucleus (DRN) are
implicated in the drug treatment and pathophysiology of a wide variety of neuropsychiatric …
implicated in the drug treatment and pathophysiology of a wide variety of neuropsychiatric …
Activation and blockade of prelimbic 5-HT6 receptors produce different effects on depressive-like behaviors in unilateral 6-hydroxydopamine-induced Parkinson's rats
YM Zhang, L Zhang, Y Wang, YN Sun, Y Guo, CX Du… - …, 2016 - Elsevier
The role of prelimbic (PrL) 5-HT 6 receptors in depression is poorly understood, particularly
in Parkinson's disease-related depression. Here we reported that 6-hydroxydopamine …
in Parkinson's disease-related depression. Here we reported that 6-hydroxydopamine …
The effects of systemic and local microinjection into the central nervous system of the selective serotonin 5-HT6 receptor agonist WAY-208466 on sleep and …
JM Monti, H Jantos, LE Schechter - Behavioural brain research, 2013 - Elsevier
The effects of WAY-208466, a selective 5-HT6 receptor agonist on spontaneous sleep were
studied in adult rats implanted for chronic sleep recordings. Systemic administration of WAY …
studied in adult rats implanted for chronic sleep recordings. Systemic administration of WAY …
Antistress Effects of Rosa rugosa Thunb. on Total Sleep Deprivation–Induced Anxiety-Like Behavior and Cognitive Dysfunction in Rat: Possible Mechanism of Action …
J Na, DR Oh, SH Han, Y Kim, EJ Choi, D Bae… - Journal of medicinal …, 2016 - liebertpub.com
Our previous results suggest that the Rosa rugosa Thunb.(family Rosaceae) alleviates
endurance exercise-induced stress by decreasing oxidative stress levels. This study aimed …
endurance exercise-induced stress by decreasing oxidative stress levels. This study aimed …
Serotonin Receptors and Antidepressants: Neuroimaging Findings from Preclinical and Clinical Research
PA Handschuh, ME Konadu, B Spurny-Dworak… - … Research Methods for …, 2022 - Springer
Major depressive disorder is an affective disease associated with a high socioeconomic
burden, social and physical impairment, as well as increased mortality rates worldwide. A …
burden, social and physical impairment, as well as increased mortality rates worldwide. A …