Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …
effector immune defense molecules in multicellular organisms. AMPs exert their …
New Treatment Options against Carbapenem-Resistant Acinetobacter baumannii Infections
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a perilous nosocomial pathogen
causing substantial morbidity and mortality. Current treatment options for CRAB are limited …
causing substantial morbidity and mortality. Current treatment options for CRAB are limited …
International consensus guidelines for the optimal use of the polymyxins: endorsed by the American college of clinical pharmacy (ACCP), European society of clinical …
BT Tsuji, JM Pogue, AP Zavascki… - … : The Journal of …, 2019 - Wiley Online Library
The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the
1950s and thus did not undergo contemporary drug development procedures. Their clinical …
1950s and thus did not undergo contemporary drug development procedures. Their clinical …
Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised …
Background Colistin–carbapenem combinations are synergistic in vitro against carbapenem-
resistant Gram-negative bacteria. We aimed to test whether combination therapy improves …
resistant Gram-negative bacteria. We aimed to test whether combination therapy improves …
Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a …
B Gutiérrez-Gutiérrez, E Salamanca… - The Lancet Infectious …, 2017 - thelancet.com
Background The best available treatment against carbapenemase-producing
Enterobacteriaceae (CPE) is unknown. The objective of this study was to investigate the …
Enterobacteriaceae (CPE) is unknown. The objective of this study was to investigate the …
Treatment of infections caused by multidrug-resistant gram-negative bacteria: Report of the British society for antimicrobial chemotherapy/healthcare infection society …
PM Hawkey, RE Warren, DM Livermore… - Journal of …, 2018 - academic.oup.com
Abstract The Working Party makes more than 100 tabulated recommendations in
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …
Escherichia coli: an old friend with new tidings
J Vila, E Sáez-López, JR Johnson… - FEMS microbiology …, 2016 - academic.oup.com
Escherichia coli is one of the most-studied microorganisms worldwide but its characteristics
are continually changing. Extraintestinal E. coli infections, such as urinary tract infections …
are continually changing. Extraintestinal E. coli infections, such as urinary tract infections …
[HTML][HTML] Antibiotic strategies in the era of multidrug resistance
G Karam, J Chastre, MH Wilcox, JL Vincent - Critical Care, 2016 - Springer
The rapid emergence and dissemination of antibiotic-resistant microorganisms in ICUs
worldwide threaten adequate antibiotic coverage of infected patients in this environment …
worldwide threaten adequate antibiotic coverage of infected patients in this environment …
Global dissemination of extensively drug‐resistant carbapenemase‐producing E nterobacteriaceae: clinical perspectives on detection, treatment and infection control
T Tängdén, CG Giske - Journal of internal medicine, 2015 - Wiley Online Library
The prevalence of carbapenem‐resistant Gram‐negative bacilli is on the rise worldwide,
posing a major public health threat. Previously, this was mostly a problem in Pseudomonas …
posing a major public health threat. Previously, this was mostly a problem in Pseudomonas …
Treatment Options for Carbapenem-Resistant Enterobacteriaceae Infections
This article provides a comprehensive review of currently available treatment options for
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …