The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a
disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by …

Burkholderia mallei and Burkholderia pseudomallei are Gram-negative organisms, which
are etiological agents of glanders and melioidosis, respectively. Although only B …

Burkholderia pseudomallei is a Gram-negative intracellular pathogen and the causative
agent of melioidosis, a severe disease of both humans and animals. Melioidosis is an …

Highlights•Burkholderia pseudomallei (BPS) possess a variety of virulence factors that
facilitate survival at different stages of intracellular infection in a variety of cell types.•At the …

Introduction: Melioidosis is a significant health problem within endemic areas such as
Southeast Asia and Northern Australia. The varied presentation of melioidosis and the …

This review provides a snapshot of chronic bacterial infections through the lens of
Burkholderia pseudomallei and detailing its ability to establish multi-nucleated giant cells …

Bacterium usually utilises type III secretion systems (T3SS) to deliver effectors directly into
host cells with the aids of chaperones. Hence, it is very important to identify bacterial T3SS …

Central nervous system (CNS) melioidosis caused by Burkholderia pseudomallei is being
increasingly reported. Because of the high mortality associated with CNS melioidosis …

Aim: We sought to characterize the contribution of the O-OTase, PglL, to virulence in two
Burkholderia spp. by comparing isogenic mutants in Burkholderia pseudomallei with the …