Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …

Insulin therapy became a reality in 1921 dramatically saving lives of people with diabetes,
but not protecting them from long-term complications. Clinically successful free islet implants …

Macroencapsulation devices provide the dual possibility of immunoprotecting transplanted
cells while also being retrievable, the latter bearing importance for safety in future trials with …

Transplantation of pancreatic islets is emerging as a successful treatment for type-1
diabetes. Its current stringent restriction to patients with critical metabolic lability is justified …

In the past two decades, many polymers have been proposed for producing
immunoprotective capsules. Examples include the natural polymers alginate, agarose …

Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease caused by the destruction of
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …

After the biotech medicine era, regenerative medicine is expected to be an advanced
medicine that is capable of curing patients with difficult-to-treat diseases and physically …

The term “liver tissue engineering” summarizes one of the ultimate goals of modern
biotechnology: the possibility of reproducing in total or in part the functions of the liver in …

At present, proven clinical treatments but no cures are available for diabetes, a global
epidemic with a huge economic burden. Transplantation of islets of Langerhans by their …

Transplantation of pancreatic islets in immune protective capsules holds the promise as a
functional cure for type 1 diabetes, also about 40 years after the first proof of principal study …