Leukocytes recruitment to thrombi supports an intimate cellular interaction leading to the
enhancement of pro-coagulant functions and pro-inflammatory responses at site of vascular …

Thrombosis is one of the major causes of mortality worldwide. Notably, it is not only
implicated in cardiovascular diseases, such as myocardial infarction (MI), stroke, and …

Thrombus formation is a complex, dynamic and multistep process, involving biochemical
reactions, mechanical stimulation, hemodynamics, and so on. In this study, we concentrate …

Objective—Circulating blood cells and endothelial cells express ectonucleoside
triphosphate diphosphohydrolase-1 (CD39) and ecto-5′-nucleotidase (CD73). CD39 …

Severe thrombosis and its ischemic consequences such as myocardial infarction, pulmonary
embolism and stroke are major worldwide health issues. The ferric chloride injury is now a …

The hemostatic response requires the tightly regulated interaction of the coagulation system,
platelets, other blood cells and components of the vessel wall at a site of vascular injury. The …

Introduction Selatogrel is a reversible antagonist of the P2Y12 receptor. In rat thrombosis/
haemostasis models, selatogrel was associated with lower blood loss than clopidogrel or …

Immune thrombocytopenia (ITP) is an autoimmune condition primarily induced by the loss of
immune tolerance to the platelet glycoproteins. Here we develop a novel flow cytometry …

Background Thromboinflammation is caused by mutual activation of platelets and
neutrophils. The site of thromboinflammation is determined by chemoattracting agents …

Background The process of thrombus formation is thought to involve interactions between
platelets and leukocytes. Leukocyte incorporation into growing thrombi has been well …