Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …

Long non-coding RNAs (lncRNAs) comprise a diverse class of RNA transcripts> 200
nucleotides in length with limited protein-coding potential. In addition to their possible role in …

The function of one-carbon metabolism is that of regulating the provision of methyl groups
for biological methylation reactions including that of DNA and histone proteins. Methylation …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

The contribution of epigenetic mechanisms to cardiovascular diseases remains poorly
understood. Hypomethylation of genomic DNA is present in human atherosclerotic lesions …

Epigenetic modifications on chromatin are most commonly thought to be involved in the
transcriptional regulation of gene expression. Due to their dependency on small-molecule …

Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …

Choline is an essential nutrient that, via its metabolite betaine, serves as a donor of methyl
groups used in fetal development to establish the epigenetic DNA and histone methylation …

Accumulating evidence suggests that long non-coding RNA H19 correlates with several
aging processes. However, the role of H19 in aging remains unclear. Many studies have …

Folates are members of the B‐class of vitamins, which are required for the synthesis of
purines and pyrimidines, and for the methylation of essential biological substances …