[HTML][HTML] Fisiopatología de la obesidad: Perspectiva actual
W Suárez-Carmona, AJ Sánchez-Oliver… - Revista chilena de …, 2017 - SciELO Chile
La obesidad es una enfermedad crónica de origen multifactorial, asociada a
complicaciones de salud potencialmente graves, y con una elevada prevalencia a nivel …
complicaciones de salud potencialmente graves, y con una elevada prevalencia a nivel …
[HTML][HTML] Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication
JB Funcke, PE Scherer - Journal of lipid research, 2019 - ASBMB
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …
Inter-organ cross-talk in metabolic syndrome
C Priest, P Tontonoz - Nature Metabolism, 2019 - nature.com
Maintenance of systemic homeostasis and the response to nutritional and environmental
challenges require the coordination of multiple organs and tissues. To respond to various …
challenges require the coordination of multiple organs and tissues. To respond to various …
[HTML][HTML] Innate Immunity Focus: Role of adipose tissue macrophages in obesity-related disorders
The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …
[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction
AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …
expanding. Just in the past decade, substantial advances have led to new insights into the …
[HTML][HTML] Endocrine role of bone in the regulation of energy metabolism
Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …
Fibroblast growth factor 21—metabolic role in mice and men
H Staiger, M Keuper, L Berti… - Endocrine …, 2017 - academic.oup.com
Since its identification in 2000, the interest of scientists in the hepatokine fibroblast growth
factor (FGF) 21 has tremendously grown, and still remains high, due to a wealth of very …
factor (FGF) 21 has tremendously grown, and still remains high, due to a wealth of very …
[HTML][HTML] Advances in understanding of the role of lipid metabolism in aging
KW Chung - Cells, 2021 - mdpi.com
During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …
Adiponectin regulation and function
H Fang, RL Judd - Comprehensive Physiology, 2011 - Wiley Online Library
Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …
large number of endocrine factors which regulate a wide variety of physiological functions …
DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway
Chronic inflammation in adipose tissue plays a key role in obesity-induced insulin
resistance. However, the mechanisms underlying obesity-induced inflammation remain …
resistance. However, the mechanisms underlying obesity-induced inflammation remain …