Regulation of cardiovascular health and disease by visceral adipose tissue‐derived metabolic hormones
Visceral adipose tissue (VAT) is a metabolic organ known to regulate fat mass, and glucose
and nutrient homeostasis. VAT is an active endocrine gland that synthesizes and secretes …
and nutrient homeostasis. VAT is an active endocrine gland that synthesizes and secretes …
[HTML][HTML] Adipocyte ceramides—the nexus of inflammation and metabolic disease
B Chaurasia, CL Talbot, SA Summers - Frontiers in immunology, 2020 - frontiersin.org
Adipose depots are heterogeneous tissues that store and sense fuel levels. Through the
secretion of lipids, cytokines, and protein hormones (adipokines), they communicate with …
secretion of lipids, cytokines, and protein hormones (adipokines), they communicate with …
[HTML][HTML] Hypothalamic AMPK as a mediator of hormonal regulation of energy balance
As a cellular energy sensor and regulator, adenosine monophosphate (AMP)-activated
protein kinase (AMPK) plays a pivotal role in the regulation of energy homeostasis in both …
protein kinase (AMPK) plays a pivotal role in the regulation of energy homeostasis in both …
[HTML][HTML] An explanation for the adiponectin paradox
HO Kalkman - Pharmaceuticals, 2021 - mdpi.com
The adipokine adiponectin improves insulin sensitivity. Functional signal transduction of
adiponectin requires at least one of the receptors AdipoR1 or AdipoR2, but additionally the …
adiponectin requires at least one of the receptors AdipoR1 or AdipoR2, but additionally the …
Biomarkers of dysfunctional visceral fat
A Gugliucci - Advances in Clinical Chemistry, 2022 - Elsevier
Dysfunctional visceral fat plays a key role in the initiation and maintenance of chronic
inflammation, liver steatosis and subsequent systemic insulin resistance that primes the …
inflammation, liver steatosis and subsequent systemic insulin resistance that primes the …
[HTML][HTML] The lncRNA H19/miR-541-3p/Wnt/β-catenin axis plays a vital role in melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells
H Han, T Tian, G Huang, D Li, S Yang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Implant dentures become the first choice for denture restoration in patients with tooth loss.
However, oral implants often fail in osteoporosis (OP) patients. Melatonin (MT) induces …
However, oral implants often fail in osteoporosis (OP) patients. Melatonin (MT) induces …
[HTML][HTML] Adiponectin in chronic kidney disease
J Przybyciński, V Dziedziejko, K Puchałowicz… - International journal of …, 2020 - mdpi.com
Adiponectin is the adipokine associated with insulin sensitization, reducing liver
gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is …
gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is …
[HTML][HTML] Adiponectin signaling pathways in liver diseases
In the liver, adiponectin regulates both glucose and lipid metabolism and exerts an insulin-
sensitizing effect. The binding of adiponectin with its specific receptors induces the activation …
sensitizing effect. The binding of adiponectin with its specific receptors induces the activation …
The obesity treatment dilemma: Why dieting is both the answer and the problem? A mechanistic overview
L Monnier, JL Schlienger, C Colette, F Bonnet - Diabetes & metabolism, 2021 - Elsevier
Restricted-calorie diets are the most worldwide used treatments for obesity. Although such
strategies are based on the first law of thermodynamics, the real life clinical practice …
strategies are based on the first law of thermodynamics, the real life clinical practice …
[HTML][HTML] Role of adiponectin in the pathogenesis of rheumatoid arthritis
K Szumilas, P Szumilas… - International journal of …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a systemic chronic inflammatory autoimmune joint disease,
characterized by progressive articular damage and joint dysfunction. One of the symptoms of …
characterized by progressive articular damage and joint dysfunction. One of the symptoms of …