Corticosteroids have numerous applications in treating inflammation and diseases of
immune function based on their significant anti-inflammatory and immunosuppressive …

Acetals and ketals and their nitrogen and sulfur homologues are often considered to be
unconventional and potentially problematic scaffolding elements or pharmacophores for the …

The pharmacological management of asthma has changed considerably in recent decades,
as it has come to be understood that it is a complex, heterogeneous disease with different …

Due to their potent anti-inflammatory capacity (particularly in predominantly eosinophilic
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …

Asthma, a chronic respiratory disease characterized by chronic airway inflammation,
bronchial hyperresponsiveness, and reversible airflow obstruction, poses a substantial …

Short-acting β2 agonists (SABAs) have been a mainstay of asthma treatment since the
1950s, and have been mainly recommended as-needed for symptom relief alongside daily …

Introduction Short-acting β2-agonist (SABA) reliever overuse is common in asthma, despite
availability of inhaled corticosteroid (ICS)-based maintenance therapies, and may be …

Chronic respiratory diseases are among the leading causes of mortality worldwide, with the
major contributor, chronic obstructive pulmonary disease (COPD) accounting for …

Background In adults and adolescents with asthma, use of≥ 3 short‐acting β2‐agonist
(SABA) canisters/year is associated with increased exacerbation risk. Whether this …

Pulmonary inflammations such as chronic obstructive pulmonary disease and cystic fibrosis
are widespread and can be fatal, especially when they are characterized by abnormal …