[HTML][HTML] Engineering exosome-based biomimetic nanovehicles for wound healing

A Joorabloo, T Liu - Journal of Controlled Release, 2023 - Elsevier
Complexity and difficulties in wound management are pressing concerns that affect patients'
quality of life and may result in tissue infection, necrosis, and loss of local and systemic …

Nanomaterials in anticancer applications and their mechanism of action-A review

CGA Das, VG Kumar, TS Dhas, V Karthick… - … , Biology and Medicine, 2023 - Elsevier
The current challenges in cancer treatment using conventional therapies have made the
emergence of nanotechnology with more advancements. The exponential growth of …

Insights into exosome transport through the blood–brain barrier and the potential therapeutical applications in brain diseases

M Abdelsalam, M Ahmed, Z Osaid, R Hamoudi… - Pharmaceuticals, 2023 - mdpi.com
Drug delivery to the central nervous system (CNS) is limited due to the presence of the blood–
brain barrier (BBB), a selective physiological barrier located at the brain microvessels that …

Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes

DN Moholkar, R Kandimalla, RC Gupta, F Aqil - Cancer Letters, 2023 - Elsevier
Cancer has recently surpassed heart disease as the leading cause of deaths worldwide for
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …

Bolstering the secretion and bioactivities of umbilical cord MSC-derived extracellular vesicles with 3D culture and priming in chemically defined media

JY Kim, WK Rhim, SG Cha, J Woo, JY Lee, CG Park… - Nano …, 2022 - Springer
Human mesenchymal stem cells (hMSCs)-derived extracellular vesicles (EVs) have been
known to possess the features of the origin cell with nano size and have shown therapeutic …

Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives

S Sen, J Xavier, N Kumar, MZ Ahmad, OP Ranjan - 3 Biotech, 2023 - Springer
Abstract Exosomes are nanosized (size~ 30–150 nm) natural vesicular structures released
from cells by physiological processes or pathological circumstances. Exosomes are growing …

Bone marrow mesenchymal stromal cells in a 3D system produce higher concentration of extracellular vesicles (EVs) with increased complexity and enhanced …

E Jalilian, H Massoumi, B Bigit, S Amin, EA Katz… - Stem Cell Research & …, 2022 - Springer
Abstract Purpose Extracellular vesicles (EVs) derived from mesenchymal stromal cells
(MSCs) have been demonstrated to possess great potential in preclinical models. An …

Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics

S Sonbhadra, Mehak, LM Pandey - Biosensors, 2023 - mdpi.com
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …

Therapeutic and diagnostic potential of exosomes as drug delivery systems in brain cancer

DI Avgoulas, KS Tasioulis, RM Papi, AA Pantazaki - Pharmaceutics, 2023 - mdpi.com
Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …

Exploring the versatility of exosomes: a review on isolation, characterization, detection methods, and diverse applications

O Altıntaş, Y Saylan - Analytical Chemistry, 2023 - ACS Publications
Extracellular vesicles (EVs) are crucial mediators of intercellular communication and can be
classified based on their physical properties, biomolecular structure, and origin. Among EVs …