Fusion of Exosomes and Nanotechnology: Cutting-Edge Cancer Theranostics

R Agnihotram, R Dhar, D Dhar… - ACS Applied Nano …, 2024 - ACS Publications
Cancer is the most challenging health complication worldwide. Scientific society has tried to
decode its complications and is developing a smart solution for mankind. Extracellular …

Nanocarrier-based targeted therapies for myocardial infarction

TA George, CC Hsu, A Meeson, DJ Lundy - Pharmaceutics, 2022 - mdpi.com
Myocardial infarction is a major cause of morbidity and mortality worldwide. Due to poor
inherent regeneration of the adult mammalian myocardium and challenges with effective …

Exosomes for angiogenesis induction in ischemic disorders

K Moeinabadi‐Bidgoli, M Rezaee… - Journal of cellular …, 2023 - Wiley Online Library
Ischaemic disorders are leading causes of morbidity and mortality worldwide. While the
current therapeutic approaches have improved life expectancy and quality of life, they are …

Emerging nano-carrier strategies for brain tumor drug delivery and considerations for clinical translation

DJ Lundy, H Nguyễn, PCH Hsieh - Pharmaceutics, 2021 - mdpi.com
Treatment of brain tumors is challenging since the blood–brain tumor barrier prevents
chemotherapy drugs from reaching the tumor site in sufficient concentrations …

Exosome-biomimetic nanocarriers for oral drug delivery

F Liu, F Meng, Z Yang, H Wang, Y Ren, Y Cai… - Chinese Chemical …, 2024 - Elsevier
Exosomes as authigenous nanovesicles secreted by living cells represent a significant class
of biomaterials. By virtue of their unique roles in intercellular communication, exosomes can …

Emerging drug delivery vectors: Engineering of Plant-Derived nanovesicles and their applications in Biomedicine

LY Yang, CQ Li, YL Zhang, MW Ma… - International Journal …, 2024 - Taylor & Francis
Extracellular vesicles can transmit intercellular information and transport biomolecules to
recipient cells during various pathophysiological processes in the organism. Animal cell …

Mesenchymal stem cells-derived secretome and extracellular vesicles: perspective and challenges in cancer therapy and clinical applications

J Gemayel, D Chaker, G El Hachem, M Mhanna… - Clinical and …, 2023 - Springer
Stem cell-based therapies have been foreshowed as a promising therapeutic approach for
the treatment of several diseases. However, in the cancer context, results obtained from …

Exosomes: a Cutting-Edge Theranostics Tool for Oral Cancer

K Kalele, S Nyahatkar, D Mirgh… - ACS Applied Bio …, 2024 - ACS Publications
Exosomes are a subpopulation of extracellular vesicles (EVs) secreted by cells. In cancer,
they are key cellular messengers during cancer development and progression. Tumor …

Unveiling novel avenues in mtor-targeted therapeutics: Advancements in glioblastoma treatment

S Singh, D Barik, K Lawrie, I Mohapatra… - International journal of …, 2023 - mdpi.com
The mTOR signaling pathway plays a pivotal and intricate role in the pathogenesis of
glioblastoma, driving tumorigenesis and proliferation. Mutations or deletions in the PTEN …

HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and …

L Corrie, S Ajjarapu, S Banda, M Parvathaneni… - Materials, 2023 - mdpi.com
Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …