[HTML][HTML] Aptamer-functionalized mesenchymal stem cells-derived exosomes for targeted delivery of SN38 to colon cancer cells

E Pishavar, R Yazdian-Robati, K Abnous… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Known as natural nanovesicles, exosomes have attracted increased attention
as biocompatible carriers throughout recent years, which can provide appropriate sources …

[HTML][HTML] Advances in stem cell therapy in Alzheimer's disease: a comprehensive clinical trial review

N Karvelas, S Bennett, G Politis, NI Kouris… - Stem cell …, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common type of dementia responsible for more than
121,499 deaths from AD in 2019 making AD the sixth-leading cause in the United States. AD …

Enzyme Engineering Strategies for the Bioenhancement of l-Asparaginase Used as a Biopharmaceutical

J Miranda, N Lefin, JF Beltran, LH Belén, A Tsipa… - BioDrugs, 2023 - Springer
Over the past few years, there has been a surge in the industrial production of recombinant
enzymes from microorganisms due to their catalytic characteristics being highly efficient …

Exosome-transmitted ANGPTL1 suppresses angiogenesis in glioblastoma by inhibiting the VEGFA/VEGFR2/Akt/eNOS pathway

D Wang, H Li, T Zeng, Q Chen, W Huang… - Journal of …, 2024 - Elsevier
Objective Glioblastoma (GBM) is a highly vascularized malignancy that relies on new vessel
generation, and thus targeting angiogenesis has been a promising anti-GBM approach …

Edible plant-derived extracellular vesicles for oral mRNA vaccine delivery

C Gai, MAC Pomatto, MC Deregibus, M Dieci, A Piga… - Vaccines, 2024 - mdpi.com
Nucleic acid delivery through extracellular vesicles (EVs) is a well-preserved evolutionary
mechanism in all life kingdoms including eukaryotes, prokaryotes, and plants. EVs naturally …

[HTML][HTML] Advances in RNA cancer therapeutics: New insight into exosomes as miRNA delivery

L Volpini, F Monaco, L Santarelli, J Neuzil… - Aspects of Molecular …, 2023 - Elsevier
We are now entering a new era of RNA therapies, such that mRNA-based vaccines and
RNA interference approaches such as siRNA have already been launched on the …

Nanotechnology for biomedical applications

SR Pasika, R Bulusu, BVK Rao, N Kommineni… - Nanomaterials …, 2023 - Springer
Nowadays, promising era for stepping towards the rapid development of the novel
nanomedicine using nanotechnology to address various difficulties facing our human …

Unveiling the promise: Exosomes as game‐changers in anti‐infective therapy

VP Chavda, G Luo, R Bezbaruah, T Kalita… - …, 2024 - Wiley Online Library
Extracellular vesicles (EVs)‐based intercellular communication (through exosomes,
microvesicles, and apoptotic bodies) is conserved across all kingdoms of life. In recent …

Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Precision Medicine

A Sharma, A Yadav, A Nandy, S Ghatak - Pharmaceutics, 2024 - mdpi.com
Of all the numerous nanosized extracellular vesicles released by a cell, the endosomal-
originated exosomes are increasingly recognized as potential therapeutics, owing to their …

[HTML][HTML] Advancement in exosome-based cancer therapeutics: a new era in cancer treatment

A Dutta, S Paul - Frontiers in Nanotechnology, 2022 - frontiersin.org
In the modern era of rapid development and advancement in cancer therapeutics and
management, there is a growing awareness in the application of exosomes as a potential …