Abstract Background The rise of Big Data-driven health research challenges the assumed
contribution of medical research to the public good, raising questions about whether the …

Background Large-scale linkage of international clinical datasets could lead to unique
insights into disease aetiology and facilitate treatment evaluation and drug development …

Experiments in geoengineering–intentionally manipulating the Earth's climate to reduce
global warming–have become the focus of a vital debate about responsible science and …

To address the ethical challenges in big data health research we propose the concept of
systemic oversight. This approach is based on six defining features (adaptivity, flexibility …

New models of data governance for health data are a focus of growing interest in an era of
challenge to the social licence. In this article, we reflect on what the data trust model, which …

Biobanks will be essential to facilitate the translation of genomic research into real
improvements to healthcare. Biobanking is a long-term commitment, requiring public support …

Open Science is calling for a radical re-thinking of existing scientific practices. Within the
neuroimaging community, Open Science practices are taking the form of open data …

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The right not to know is a contested matter. This can be because the inversion of the normal
framing of entitlement to information about one's own health is thought to be illogical and …

Low levels of public trust in biobanks are perceived to be a deterrent to participation and a
threat to their sustainability. Acting in a “trustworthy” manner is seen to be one approach to …