[HTML][HTML] Engineered three-dimensional scaffolds for enhanced bone regeneration in osteonecrosis
T Zhu, Y Cui, M Zhang, D Zhao, G Liu, J Ding - Bioactive materials, 2020 - Elsevier
Osteonecrosis, which is typically induced by trauma, glucocorticoid abuse, or alcoholism, is
one of the most severe diseases in clinical orthopedics. Osteonecrosis often leads to joint …
one of the most severe diseases in clinical orthopedics. Osteonecrosis often leads to joint …
[HTML][HTML] The many facets of erythropoietin physiologic and metabolic response
S Suresh, PK Rajvanshi, CT Noguchi - Frontiers in physiology, 2020 - frontiersin.org
In mammals, erythropoietin (EPO), produced in the kidney, is essential for bone marrow
erythropoiesis, and hypoxia induction of EPO production provides for the important …
erythropoiesis, and hypoxia induction of EPO production provides for the important …
New insights for oxidative stress and diabetes mellitus
K Maiese - Oxidative medicine and cellular longevity, 2015 - Wiley Online Library
The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …
Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders
K Maiese - British journal of clinical pharmacology, 2016 - Wiley Online Library
Neurodegenerative disorders are significantly increasing in incidence as the age of the
global population continues to climb with improved life expectancy. At present, more than 30 …
global population continues to climb with improved life expectancy. At present, more than 30 …
mTOR: on target for novel therapeutic strategies in the nervous system
K Maiese, ZZ Chong, YC Shang, S Wang - Trends in molecular medicine, 2013 - cell.com
The mammalian target of rapamycin (mTOR), the key component of the protein complexes
mTORC1 and mTORC2, plays a critical role in cellular development, tissue regeneration …
mTORC1 and mTORC2, plays a critical role in cellular development, tissue regeneration …
NGF-p75 signaling coordinates skeletal cell migration during bone repair
Bone regeneration following injury is initiated by inflammatory signals and occurs in
association with infiltration by sensory nerve fibers. Together, these events are believed to …
association with infiltration by sensory nerve fibers. Together, these events are believed to …
Bone and skeletal muscle: key players in mechanotransduction and potential overlapping mechanisms
CA Goodman, TA Hornberger, AG Robling - Bone, 2015 - Elsevier
The development and maintenance of skeletal muscle and bone mass is critical for
movement, health and issues associated with the quality of life. Skeletal muscle and bone …
movement, health and issues associated with the quality of life. Skeletal muscle and bone …
Silk fibroin/collagen/hydroxyapatite scaffolds obtained by 3D printing technology and loaded with recombinant human erythropoietin in the reconstruction of alveolar …
H Liu, C Wang, X Sun, C Zhan, Z Li, L Qiu… - ACS biomaterials …, 2022 - ACS Publications
The fast osteogenesis of the large alveolar fossa and the maintenance of the height of the
alveolar ridge after tooth extraction have always been a clinical challenge. Therefore, this …
alveolar ridge after tooth extraction have always been a clinical challenge. Therefore, this …
[HTML][HTML] Hypoxia-inducible factors signaling in osteogenesis and skeletal repair
Q Qin, Y Liu, Z Yang, M Aimaijiang, R Ma… - International Journal of …, 2022 - mdpi.com
Sufficient oxygen is required to maintain normal cellular and physiological function, such as
a creature's development, breeding, and homeostasis. Lately, some researchers have …
a creature's development, breeding, and homeostasis. Lately, some researchers have …
Targeting disease through novel pathways of apoptosis and autophagy
K Maiese, ZZ Chong, YC Shang… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Apoptosis and autophagy impact cell death in multiple systems of the body.
Development of new therapeutic strategies that target these processes must address their …
Development of new therapeutic strategies that target these processes must address their …