[PDF][PDF] Toll-like receptors and the control of immunity
KA Fitzgerald, JC Kagan - Cell, 2020 - cell.com
The study of innate immunity and its link to inflammation and host defense encompasses
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …
Function and biogenesis of lipopolysaccharides
B Bertani, N Ruiz - Ecosal plus, 2018 - Am Soc Microbiol
The cell envelope is the first line of defense between a bacterium and the world-at-large.
Often, the initial steps that determine the outcome of chemical warfare, bacteriophage …
Often, the initial steps that determine the outcome of chemical warfare, bacteriophage …
[HTML][HTML] Evolution of immune genes is associated with the Black Death
Infectious diseases are among the strongest selective pressures driving human evolution,.
This includes the single greatest mortality event in recorded history, the first outbreak of the …
This includes the single greatest mortality event in recorded history, the first outbreak of the …
Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
Limited proteolysis of gasdermin D (GSDMD) generates an N-terminal pore-forming
fragment that controls pyroptosis in macrophages. GSDMD is processed via inflammasome …
fragment that controls pyroptosis in macrophages. GSDMD is processed via inflammasome …
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
Cell death and inflammation are intimately linked during Yersinia infection. Pathogenic
Yersinia inhibits the MAP kinase TGFβ-activated kinase 1 (TAK1) via the effector YopJ …
Yersinia inhibits the MAP kinase TGFβ-activated kinase 1 (TAK1) via the effector YopJ …
Klebsiella pneumoniae infection biology: living to counteract host defences
JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …
Circulating platelets as mediators of immunity, inflammation, and thrombosis
M Koupenova, L Clancy, HA Corkrey… - Circulation …, 2018 - Am Heart Assoc
Platelets, non-nucleated blood components first described over 130 years ago, are
recognized as the primary cell regulating hemostasis and thrombosis. The vascular …
recognized as the primary cell regulating hemostasis and thrombosis. The vascular …
Klebsiella pneumoniae: going on the offense with a strong defense
MK Paczosa, J Mecsas - Microbiology and molecular biology …, 2016 - Am Soc Microbiol
Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …
Yersinia pestis: the natural history of plague
R Barbieri, M Signoli, D Chevé… - Clinical microbiology …, 2020 - Am Soc Microbiol
SUMMARY The Gram-negative bacterium Yersinia pestis is responsible for deadly plague, a
zoonotic disease established in stable foci in the Americas, Africa, and Eurasia. Its …
zoonotic disease established in stable foci in the Americas, Africa, and Eurasia. Its …
[HTML][HTML] Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics
CE Demeure, O Dussurget, G Mas Fiol… - Genes & …, 2019 - nature.com
Plague is a vector-borne disease caused by Yersinia pestis. Transmitted by fleas from
rodent reservoirs, Y. pestis emerged< 6000 years ago from an enteric bacterial ancestor …
rodent reservoirs, Y. pestis emerged< 6000 years ago from an enteric bacterial ancestor …