Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment

M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

[HTML][HTML] A novel axis of circKIF4A-miR-637-STAT3 promotes brain metastasis in triple-negative breast cancer

S Wu, J Lu, H Zhu, F Wu, Y Mo, L Xie, C Song, L Liu… - Cancer Letters, 2024 - Elsevier
Among patients with triple-negative breast cancer (TNBC), distant metastasis is the leading
cause of death. Our previous studies have shown that TNBC progression is greatly …

Exosomal circRNAs: Novel biomarkers and therapeutic targets for urinary tumors

Q Liu, S Li - Cancer Letters, 2024 - Elsevier
Exosomal circRNAs have emerged as promising biomarkers and therapeutic targets for
urinary tumors. In this review, we explored the intricate role of exosomal circRNAs in …

[HTML][HTML] Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes

H Liu, L Tang, Y Li, W Xie, L Zhang, H Tang, T Xiao… - Molecular Cancer, 2024 - Springer
The incidence of nasopharyngeal carcinoma (NPC) exhibits significant variations across
different ethnic groups and geographical regions, with Southeast Asia and North Africa …

[HTML][HTML] Causal relationship between immune cells and prostate cancer: a Mendelian randomization study

Z Ye, X Deng, J Zhang, R Shao, C Song… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Despite the abundance of research indicating the participation of immune cells
in prostate cancer development, establishing a definitive cause-and-effect relationship has …

[HTML][HTML] Circular RNA in cervical cancer: Fundamental mechanism and clinical potential

S Begliarzade, A Sufianov, T Ilyasova… - Non-coding RNA …, 2023 - Elsevier
CC (CC) remains a significant global health concern, imposing a substantial health burden
on women worldwide due to its high incidence and mortality rates. To address this issue …

[HTML][HTML] Regulatory mechanism and promising clinical application of exosomal circular RNA in gastric cancer

M Han, M Zhang, M Qi, Y Zhou, F Li, S Fang - Frontiers in Oncology, 2023 - frontiersin.org
Gastric cancer (GC) is one of the most common malignancies worldwide and the leading
cause of cancer-related deaths. Exosomes are nanoscale extracellular vesicles secreted by …

RNA-cleaving DNAzymes for accurate biosensing and gene therapy

X Gao, Y Liu, W Huo, Y Song, Y Chen, J Zhang, X Yang… - Nanoscale, 2023 - pubs.rsc.org
RNA-cleaving DNAzymes, which are single-stranded catalytic DNA, have attracted
considerable attention in bioanalysis and biomedical applications because of their high …

[HTML][HTML] New insights into the potential of exosomal circular RNAs in mediating cancer chemotherapy resistance and their clinical applications

Q Li, Y Zhang, P Jin, Y Chen, C Zhang, X Geng… - Biomedicine & …, 2024 - Elsevier
Chemotherapy resistance typically leads to tumour recurrence and is a major obstacle to
cancer treatment. Increasing numbers of circular RNAs (circRNAs) have been confirmed to …

[HTML][HTML] Long non-coding RNA GAS5 promotes cisplatin-chemosensitivity of osteosarcoma cells via microRNA-26b-5p/TP53INP1 axis

G Li, X Yan - Journal of Orthopaedic Surgery and Research, 2023 - Springer
Osteosarcoma is a common malignant bone tumor. Cisplatin (DDP) achieves a high
response rate in osteosarcoma. Here we aim to study the dysregulation of long non-coding …