Oral cancers are among the common head and neck malignancies. Different anticancer
therapy modalities such as chemotherapy, immunotherapy, radiation therapy, and also …

Preclinical models of cancer have long been paramount to understanding tumor
development and advancing the treatment of cancer. Creating preclinical models that mimic …

Anti-PD-1/PD-L1 therapy has shown significant benefits in the treatment of a variety of
malignancies. However, not all cancer patients can benefit from this strategy due to drug …

Oral cavity carcinomas are the most frequent malignancies among head and neck
malignancies. Oral tumors include not only oral cancer cells with different potency and …

Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …

Hepatocellular carcinoma (HCC) is recognized as the fifth most common cancer and the
third most common cause of death in Asian population. Studies reported that HCC is …

Cancer-associated fibroblasts (CAFs) are a key component of the tumor microenvironment
and are essential for tumorigenesis and development. Regorafenib is a multikinase inhibitor …

As the prognosis for squamous cell carcinoma of the head and neck remains unsatisfactory
when compared to other malignancies, novel therapies targeting specific biomarkers are a …

Simple Summary Soft tissue sarcomas represent a large heterogeneous group of malignant
neoplasms that are characterized by a poor disease outcome and being poorly studied …

Introduction The prognosis of advanced esophageal squamous cell carcinoma (ESCC) is
poor. Although cytotoxic drugs have been widely used in advanced ESCC, several antibody …