[HTML][HTML] Renal tubular epithelial cells: the neglected mediator of tubulointerstitial fibrosis after injury

R Qi, C Yang - Cell death & disease, 2018 - nature.com
Renal fibrosis, especially tubulointerstitial fibrosis, is the inevitable outcome of all
progressive chronic kidney diseases (CKDs) and exerts a great health burden worldwide …

[HTML][HTML] The molecular mechanisms of hemodialysis vascular access failure

A Brahmbhatt, A Remuzzi, M Franzoni, S Misra - Kidney international, 2016 - Elsevier
The arteriovenous fistula has been used for more than 50 years to provide vascular access
for patients undergoing hemodialysis. More than 1.5 million patients worldwide have end …

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

JJ Frere, RA Serafini, KD Pryce, M Zazhytska… - Science translational …, 2022 - science.org
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

[HTML][HTML] Development and evaluation of deep learning–based segmentation of histologic structures in the kidney cortex with multiple histologic stains

CP Jayapandian, Y Chen, AR Janowczyk, MB Palmer… - Kidney international, 2021 - Elsevier
The application of deep learning for automated segmentation (delineation of boundaries) of
histologic primitives (structures) from whole slide images can facilitate the establishment of …

[HTML][HTML] Programmed cell death in diabetic nephropathy: a review of apoptosis, autophagy, and necroptosis

NS Erekat - Medical Science Monitor: International Medical Journal …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …

[HTML][HTML] Flavonoids in treatment of chronic kidney disease

YL Cao, JH Lin, HP Hammes, C Zhang - Molecules, 2022 - mdpi.com
Chronic kidney disease (CKD) is a progressive systemic disease, which changes the
function and structure of the kidneys irreversibly over months or years. The final common …

[HTML][HTML] Molecular mechanisms of kidney injury and repair

S Rayego-Mateos, L Marquez-Expósito… - International journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus
emphasizing the need to better understand the molecular mechanisms of damage and …

[HTML][HTML] Alport syndrome classification and management

BA Warady, R Agarwal, S Bangalore, A Chapman… - Kidney medicine, 2020 - Elsevier
Alport syndrome affects up to 60,000 people in the United States. The proposed
reclassification of thin basement membrane nephropathy and some cases of focal …

[HTML][HTML] Progression of chronic kidney disease: too much cellular talk causes damage

L Gewin, R Zent, A Pozzi - Kidney international, 2017 - Elsevier
Tubulointerstitial fibrosis, tubular atrophy, and peritubular capillary rarefaction are major
hallmarks of chronic kidney disease. The tubulointerstitium consists of multiple cell …

[HTML][HTML] The contribution of lipotoxicity to diabetic kidney disease

JR Schelling - Cells, 2022 - mdpi.com
Lipotoxicity is a fundamental pathophysiologic mechanism in diabetes and non-alcoholic
fatty liver disease and is now increasingly recognized in diabetic kidney disease (DKD) …