Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …

Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

Annotating the molecular basis of human disease remains an unsolved challenge, as 93%
of disease loci are non-coding and gene-regulatory annotations are highly incomplete …

Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant
portion of the worldwide population. Aging of schizophrenia patients is associated with …

It is well established that the organ damage that complicates human diabetes is caused by
prolonged hyperglycemia, but the cellular and molecular mechanisms by which high levels …

Aims Heart failure (HF) is a major public health concern worldwide. The diversity of HF
makes it challenging to decipher the underlying complex pathological processes using …

The innate immune system is the first line of host defense against infection and is comprised
of humoral and cellular mechanisms that recognize potential pathogens within minutes or …

Failure of the right ventricle plays a critical role in any type of heart failure. However, the
mechanism remains unclear, and there is no specific therapy. Here, we show that the right …

This study was undertaken to uncover the regulatory role of lycopene in targeting
lipopolysaccharide (LPS) induced oxidative stress and inflammatory cascades and …

Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and significantly
increases the risks of morbidity, mortality and health care expenditure; however, treatment …