Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action

R Mani, V Natesan - Phytochemistry, 2018 - Elsevier
In recent years, public and scientific interest in plant flavonoids has tremendously increased
because of their postulated health benefits. This review was mainly focuses on the flavone …

Nutraceuticals for the treatment of diabetic retinopathy

MG Rossino, G Casini - Nutrients, 2019 - mdpi.com
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus and
is characterized by degeneration of retinal neurons and neoangiogenesis, causing a severe …

Characteristics and glucose uptake promoting effect of chrysin-loaded phytosomes prepared with different phospholipid matrices

SM Kim, JI Jung, C Chai, JY Imm - Nutrients, 2019 - mdpi.com
Chrysin-loaded phytosomes (CP) were prepared using either soya phosphatidylcholine
(SPC) or egg phospholipid (EPL) by the solvent evaporation method. Different phospholipid …

Chrysin reduces oxidative stress but does not affect polyol pathway in the lenses of type 1 diabetic rats

W Wojnar, M Zych, S Borymski, I Kaczmarczyk-Sedlak - Antioxidants, 2020 - mdpi.com
Prolonged hyperglycemia is one of the main causes of reactive oxygen species and free
radicals generation in diabetes which may affect various organs, including the eye …

Impact of chrysin on the molecular mechanisms underlying diabetic complications

T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
Diabetes mellitus is a chronic metabolic disorder, resulting in high morbidity and mortality
worldwide. Neuropathy, ocular diseases, kidney diseases, and cardiovascular disease are …

Inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor by chrysin in a rat model of choroidal neovascularization

JH Song, KY Moon, SC Lee, SS Kim - International journal of molecular …, 2020 - mdpi.com
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss
among the elderly population. Vascular endothelial growth factor (VEGF) is essential for …

Polyphenols and posterior segment eye diseases: effects on angiogenesis, invasion, migration and epithelial-mesenchymal transition

M Caban, U Lewandowska - Food Reviews International, 2023 - Taylor & Francis
Posterior segment eye diseases are a major cause of visual impairment worldwide. If left
untreated, most of them lead to partial or complete blindness. The formation of new …

[HTML][HTML] Investigation of the antioxidant effect of Chrysin in an experimental cataract model created in chick embryos

GA Kurt, T Ertekin, E Atay, A Bilir, HB Koca… - Molecular …, 2023 - ncbi.nlm.nih.gov
Purpose: Cataract, which occurs as a result of lens opacification, is one of the most common
causes of vision loss. In the literature, deterioration of the antioxidant system due to the …

Chrysin alleviates DNA damage to improve disturbed immune homeostasis and pro-angiogenic environment in laser-induced choroidal neovascularization

J Wang, Z Wang, J Liu, M Zhou, H Wang, H Zhu… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Choroidal neovascularization (CNV) is a devastating pathology of numerous ocular
diseases, such as wet age-related macular degeneration (wAMD), which causes irreversible …

[HTML][HTML] Chrysin increased progesterone and LH levels, estrous phase duration and altered uterine histology without affecting aromatase expression in rat ovary

MA Abbas, KM Alqaisi, A Disi, NA Hameed - Journal of Functional Foods, 2022 - Elsevier
The effect of chrysin, a flavonoid found in Passiflora spp., honey and propolis on female sex
hormones and on ovarian and uterine histology was studied. Treatment of Wistar rats with …