Critical role of hypoxia sensor-HIF-1α in VEGF gene activation. Implications for angiogenesis and tissue injury healing
A Ahluwalia, AS Tarnawski - Current medicinal chemistry, 2012 - ingentaconnect.com
Vascular injury of esophageal and gastrointestinal mucosa caused by injurious and
ulcerogenic factors leads to the cessation of blood flow, ischemia, and hypoxia and tissue …
ulcerogenic factors leads to the cessation of blood flow, ischemia, and hypoxia and tissue …
Importin α: functions as a nuclear transport factor and beyond
M Oka, Y Yoneda - Proceedings of the Japan Academy, Series B, 2018 - jstage.jst.go.jp
Nucleocytoplasmic transport is an essential process in eukaryotes. The molecular
mechanisms underlying nuclear transport that involve the nuclear transport receptor, small …
mechanisms underlying nuclear transport that involve the nuclear transport receptor, small …
[HTML][HTML] COMPARTMENTS: unification and visualization of protein subcellular localization evidence
Information on protein subcellular localization is important to understand the cellular
functions of proteins. Currently, such information is manually curated from the literature …
functions of proteins. Currently, such information is manually curated from the literature …
Tracking STAT nuclear traffic
NC Reich, L Liu - Nature Reviews Immunology, 2006 - nature.com
Accurate cellular localization is crucial for the effective function of most signalling molecules
and nuclear translocation is central to the function of transcription factors. The passage of …
and nuclear translocation is central to the function of transcription factors. The passage of …
The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation
D Kawamori, H Kaneto, Y Nakatani, T Matsuoka… - Journal of Biological …, 2006 - ASBMB
It has been shown that oxidative stress and activation of the c-Jun N-terminal kinase (JNK)
pathway induce the nucleocytoplasmic translocation of the pancreatic transcription factor …
pathway induce the nucleocytoplasmic translocation of the pancreatic transcription factor …
Dual functional roles of dentin matrix protein 1: implications in biomineralization and gene transcription by activation of intracellular Ca2+ store
K Narayanan, A Ramachandran, J Hao, G He… - Journal of Biological …, 2003 - ASBMB
Dentin matrix protein 1 (DMP1) is a bone-and teeth-specific protein initially identified from
mineralized dentin. Here we report that DMP1 is primarily localized in the nuclear …
mineralized dentin. Here we report that DMP1 is primarily localized in the nuclear …
Oxidative Stress Induces Nucleo-Cytoplasmic Translocation of Pancreatic Transcription Factor PDX-1 Through Activation of c-Jun NH2-terminal Kinase
D Kawamori, Y Kajimoto, H Kaneto, Y Umayahara… - Diabetes, 2003 - Am Diabetes Assoc
Oxidative stress is induced in pancreatic β-cells under diabetic conditions and causes β-cell
dysfunction. Antioxidant treatment of diabetic animals leads to recovery of insulin …
dysfunction. Antioxidant treatment of diabetic animals leads to recovery of insulin …
Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination
Humans have seven APOBEC3 DNA cytosine deaminases. The activity of these enzymes
allows them to restrict a variety of retroviruses and retrotransposons, but may also cause pro …
allows them to restrict a variety of retroviruses and retrotransposons, but may also cause pro …
Nuclear localization of the Nipah virus W protein allows for inhibition of both virus-and toll-like receptor 3-triggered signaling pathways
The Nipah virus V and W proteins, which are encoded by the P gene via RNA editing, have
a common N-terminal domain but unique C-terminal domains. They localize to the …
a common N-terminal domain but unique C-terminal domains. They localize to the …
Triggering neural differentiation of ES cells by subtype switching of importin-α
N Yasuhara, N Shibazaki, S Tanaka, M Nagai… - Nature cell …, 2007 - nature.com
Nuclear proteins are selectively imported into the nucleus by transport factors such as
importin-α and importin-β,. Here, we show that the expression of importin-α subtypes is …
importin-α and importin-β,. Here, we show that the expression of importin-α subtypes is …