Early-onset treadmill training reduces mechanical allodynia and modulates calcitonin gene-related peptide fiber density in lamina III/IV in a mouse model of spinal …

TA Nees, A Tappe-Theodor, C Sliwinski, M Motsch… - Pain, 2016 - journals.lww.com
Below-level central neuropathic pain (CNP) affects a large proportion of spinal cord injured
individuals. To better define the dynamic changes of the spinal cord neural network …

Differential pain modulation properties in central neuropathic pain after spinal cord injury

H Gruener, G Zeilig, Y Laufer, N Blumen, R Defrin - Pain, 2016 - journals.lww.com
It seems that central neuropathic pain (CNP) is associated with altered abilities to modulate
pain; whereas dysfunction in descending pain inhibition is associated with the extent of …

Mental imagery as a rehabilitative therapy for neuropathic pain in people with spinal cord injury: a randomized controlled trial

J Kaur, S Ghosh, AK Sahani… - … and Neural Repair, 2020 - journals.sagepub.com
Background Pain of neuropathic origin in spinal cord injury (SCI) is unbearable and
challenging to treat. Research studies conducted in the past have shown that mental …

Bioinformatics genes and pathway analysis for chronic neuropathic pain after spinal cord injury

G Zhang, P Yang - BioMed research international, 2017 - Wiley Online Library
It is well known spinal cord injury (SCI) can cause chronic neuropathic pain (NP); however
its underlying molecular mechanisms remain elusive. This study aimed to disclose …

Prediction of central neuropathic pain in spinal cord injury based on EEG classifier

A Vuckovic, VJF Gallardo, M Jarjees, M Fraser… - Clinical …, 2018 - Elsevier
Objectives To create a classifier based on electroencephalography (EEG) to identify spinal
cord injured (SCI) participants at risk of developing central neuropathic pain (CNP) by …

Progression of neuropathic pain after acute spinal cord injury: a meta-analysis and framework for clinical trials

FM Warner, JJ Cragg, CR Jutzeler… - Journal of …, 2018 - liebertpub.com
The translation of therapeutic interventions to humans with spinal cord injury with the goal of
promoting growth and repair in the central nervous system could, inadvertently, drive …

Ten-year safety of pluripotent stem cell transplantation in acute thoracic spinal cord injury

SL McKenna, R Ehsanian, CY Liu… - … of Neurosurgery: Spine, 2022 - thejns.org
OBJECTIVE The purpose of this study was to evaluate the safety of oligodendrocyte
progenitor cells (LCTOPC1) derived from human pluripotent stem cells administered …

Neuropathic pain and spinal cord injury: management, phenotypes, and biomarkers

E Widerström-Noga - Drugs, 2023 - Springer
Chronic neuropathic pain after a spinal cord injury (SCI) continues to be a complex condition
that is difficult to manage due to multiple underlying pathophysiological mechanisms and the …

Biomarkers for predicting central neuropathic pain occurrence and severity after spinal cord injury: results of a long-term longitudinal study

H Gruener, G Zeilig, E Gaidukov, O Rachamim-Katz… - Pain, 2020 - journals.lww.com
Central neuropathic pain (CNP) after spinal cord injury (SCI) is debilitating and immensely
impacts the individual. Central neuropathic pain is relatively resistant to treatment …

Receptor-interacting protein kinase 3 inhibition relieves mechanical allodynia and suppresses NLRP3 inflammasome and NF-κB in a rat model of spinal cord injury

S Xue, Z Cao, J Wang, Q Zhao, J Han… - Frontiers in molecular …, 2022 - frontiersin.org
Background Neuroinflammation is critical in developing and maintaining neuropathic pain
after spinal cord injury (SCI). The receptor-interacting protein kinase 3 (RIPK3) has been …