Neuroinflammation in bipolar depression

F Benedetti, V Aggio, ML Pratesi, G Greco… - Frontiers in …, 2020 - frontiersin.org
Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …

GPCR-mediated signaling of metabolites

AS Husted, M Trauelsen, O Rudenko, SA Hjorth… - Cell metabolism, 2017 - cell.com
In addition to their bioenergetic intracellular function, several classical metabolites act as
extracellular signaling molecules activating cell-surface G-protein-coupled receptors …

Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?

M Blüher - Clinical science, 2016 - portlandpress.com
The worldwide obesity epidemic has become a major health concern, because it contributes
to higher mortality due to an increased risk for noncommunicable diseases including …

Crosstalk between adipose tissue insulin resistance and liver macrophages in non-alcoholic fatty liver disease

C Rosso, K Kazankov, R Younes, S Esmaili… - Journal of …, 2019 - Elsevier
Background & Aims The pathogenesis of non-alcoholic fatty liver disease (NAFLD) and
steatohepatitis (NASH) is likely due to the interaction between a deranged metabolic milieu …

[PDF][PDF] The role of senescence in the development of nonalcoholic fatty liver disease and progression to nonalcoholic steatohepatitis

AM Papatheodoridi, L Chrysavgis, M Koutsilieris… - …, 2020 - Wiley Online Library
In recent years, cellular senescence has generated a lot of interest among researchers
because of its involvement in both the normal aging process and common human diseases …

Adipose tissue inflammation and metabolic syndrome. The proactive role of probiotics

S Torres, E Fabersani, A Marquez… - European journal of …, 2019 - Springer
Purpose The first part of this review focuses on the role of cells and molecules of adipose
tissue involved in metabolic syndrome-induced inflammation and in the maintenance of this …

The cellular and molecular basis of translational immunometabolism

GD Norata, G Caligiuri, T Chavakis, G Matarese… - Immunity, 2015 - cell.com
The immune response requires major changes to metabolic processes, and indeed, energy
metabolism and functional activation are fully integrated in immune cells to determine their …

Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease

H Abdala-Valencia, ME Coden… - Journal of leukocyte …, 2018 - academic.oup.com
Eosinophils play homeostatic roles in different tissues and are found in several organs at a
homeostatic baseline, though their tissue numbers increase significantly in development …

Liver endothelial cells in NAFLD and transition to NASH and HCC

RI Velliou, AI Legaki, P Nikolakopoulou… - Cellular and Molecular …, 2023 - Springer
Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of
metabolic syndrome, which is characterised by obesity, insulin resistance …

The role of immune cells in metabolism-related liver inflammation and development of non-alcoholic steatohepatitis (NASH)

M Nati, D Haddad, AL Birkenfeld, CA Koch… - Reviews in Endocrine …, 2016 - Springer
The low grade inflammatory state present in obesity promotes the progression of Non-
Alcoholic Fatty Liver Disease (NAFLD). In Non-Alcoholic Steatohepatitis (NASH) …