Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways

BC Phukan, R Roy, I Gahatraj… - Phytotherapy …, 2023 - Wiley Online Library
Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …

[HTML][HTML] Essential oil molecules can break the loop of oxidative stress in neurodegenerative diseases

E Spisni, MC Valerii, ML Massimino - Biology, 2023 - mdpi.com
Simple Summary Neurodegenerative diseases (NDs) affect millions of people worldwide.
The combination of genes and environment, associated with age, contributes to the risk of …

[HTML][HTML] Enhancing anti-tumorigenic efficacy of eugenol in human colon cancer cells using enzyme-responsive nanoparticles

N Wijewantha, S Sane, M Eikanger, RM Antony… - Cancers, 2023 - mdpi.com
Simple Summary The migratory and invasive pathways that evolve in the early stage of
colorectal cancer (CRC) are crucial in developing the metastatic cascade and drug …

[HTML][HTML] Conjugation, prodrug, and co-administration strategies in support of nanotechnologies to improve the therapeutic efficacy of phytochemicals in the central …

G Rassu, M Sorrenti, L Catenacci, B Pavan, L Ferraro… - Pharmaceutics, 2023 - mdpi.com
Phytochemicals, produced as secondary plant metabolites, have shown interesting potential
therapeutic activities against neurodegenerative diseases and cancer. Unfortunately, poor …

[HTML][HTML] Neuroprotective Benefits of Rosmarinus officinalis and Its Bioactives against Alzheimer's and Parkinson's Diseases

D Kosmopoulou, MP Lafara, T Adamantidi… - Applied Sciences, 2024 - mdpi.com
Featured Application Utilization of Rosmarinus officinalis extracts and/or its bioactives as
ingredients in functional products, foods, cosmetics, and pharmaceuticals, with anti …

[HTML][HTML] Chlorogenic acid permeation across intestinal cell monolayers: Influence by circadian rhythms in the presence of other natural polyphenols and by …

G Botti, B Pavan, A Bianchi, L Ferraro… - Journal of Functional …, 2024 - Elsevier
Poor oral bioavailability limits chlorogenic acid (CGA) benefits on the gut-brain axis. In this
study we demonstrate the existence of an active circadian-dependent efflux for the CGA …

Exploring promising minor natural phenolic compounds in neuroprotection‐related preclinical models

CF Moreira Vasconcelos… - Basic & Clinical …, 2024 - Wiley Online Library
Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are
characterised by the progressive loss of specific neuronal cell populations due to …

D-limonene inhibits peritoneal adhesion formation in rats via anti-inflammatory, anti-angiogenic, and antioxidative effects

A Razazi, A Kakanezhadi, A Raisi, B Pedram… - …, 2024 - Springer
The aim of this research was to investigate the effects of d-limonene on decreasing post-
operative adhesion in rats and to understand the mechanisms involved. Peritoneal …

Developing Mesoporous Silica Nanoparticle-Based Stimuli-Responsive Nanocarriers for Delivery of Small Molecule Therapeutics Against Colon Cancer Cells

N Wijewantha - 2023 - search.proquest.com
This dissertation delves into the innovative application of mesoporous silica nanoparticles
(MSNs) for targeted drug delivery in colorectal cancer (CRC), one of the most prevalent and …