The concept of stimulating the body's immune response is the basis underlying vaccination.
Vaccines act by initiating the innate immune response and activating antigen presenting …

Pertussis is a severe respiratory infection caused by Bordetella pertussis, and in 2008,
pertussis was associated with an estimated 16 million cases and 195,000 deaths globally …

Pertussis is a highly contagious respiratory illness caused by the bacterial pathogen
Bordetella pertussis. Pertussis rates in the United States have been rising and reached a 50 …

Pertussis or whooping cough has persisted and resurged in the face of vaccination and has
become one of the most prevalent vaccine-preventable diseases in Western countries. The …

To the Editor: I would like to report an incomplete financial disclosure related to a Viewpoint
published in JAMA. 1 While the topic of the Viewpoint was complementary and alternative …

Background. Despite widespread childhood vaccination against Bordetella pertussis,
disease remains prevalent. It has been suggested that acellular vaccine may be less …

BACKGROUND AND OBJECTIVES: Pertussis incidence is increasing, possibly due to the
introduction of acellular vaccines, which may have decreased the durability of immune …

Background Resurgence of pertussis in the post-vaccination era has been reported in
Western countries. A shift of cases from school-age children to adolescents, adults and …

Current acellular pertussis (aP) vaccines induce strong antibody and Th2 responses but fail
to protect against nasal colonization and transmission of Bordetella pertussis. Furthermore …

Background. Unexpected waning of immunity after pertussis vaccination is now well
described. In this study we examined whether prior vaccination with whole-cell pertussis …