The value of antimicrobial peptides in the age of resistance
M Magana, M Pushpanathan, AL Santos… - The lancet infectious …, 2020 - thelancet.com
Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …
Antibiofilm activity of host defence peptides: complexity provides opportunities
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …
effector immune defense molecules in multicellular organisms. AMPs exert their …
Mechanisms of action for antimicrobial peptides with antibacterial and antibiofilm functions
N Raheem, SK Straus - Frontiers in microbiology, 2019 - frontiersin.org
The antibiotic crisis has led to a pressing need for alternatives such as antimicrobial
peptides (AMPs). Recent work has shown that these molecules have great potential not only …
peptides (AMPs). Recent work has shown that these molecules have great potential not only …
Recent innovations in bacterial infection detection and treatment
C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
L‐Arg‐Rich Amphiphilic Dendritic Peptide as a Versatile NO Donor for NO/Photodynamic Synergistic Treatment of Bacterial Infections and Promoting Wound Healing
J Zhu, J Tian, C Yang, J Chen, L Wu, M Fan, X Cai - Small, 2021 - Wiley Online Library
The development of alternative strategies for the efficient treatment of subcutaneous
abscesses that do not require the massive use of antibiotics and surgical intervention is …
abscesses that do not require the massive use of antibiotics and surgical intervention is …
Layer-by-layer biomaterials for drug delivery
D Alkekhia, PT Hammond… - Annual review of …, 2020 - annualreviews.org
Controlled drug delivery formulations have revolutionized treatments for a range of health
conditions. Over decades of innovation, layer-by-layer (LbL) self-assembly has emerged as …
conditions. Over decades of innovation, layer-by-layer (LbL) self-assembly has emerged as …
Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies
S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …