Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management
Disease overview Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell
cancer characterized by unbridled proliferation of malignant marrow stem cells with …
cancer characterized by unbridled proliferation of malignant marrow stem cells with …
[HTML][HTML] Diagnosis and treatment of therapy-related acute myeloid leukemia
SA Strickland, N Vey - Critical reviews in oncology/hematology, 2022 - Elsevier
Therapy-related acute myeloid leukemia (t-AML), defined as AML arising from prior
cytotoxic, radiation, or immunosuppressive therapy for an unrelated disease, accounts for …
cytotoxic, radiation, or immunosuppressive therapy for an unrelated disease, accounts for …
Outcomes in Patients with Poor-Risk Cytogenetics with or without TP53 Mutations Treated with Venetoclax and Azacitidine
Purpose: To evaluate efficacy and safety of venetoclax+ azacitidine in treatment-naïve
patients with acute myeloid leukemia harboring poor-risk cytogenetics and TP53 mut or …
patients with acute myeloid leukemia harboring poor-risk cytogenetics and TP53 mut or …
Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia
AH Matthews, AE Perl, SM Luger, AW Loren… - Blood …, 2022 - ashpublications.org
CPX-351 and venetoclax and azacitidine (ven/aza) are both indicated as initial therapy for
acute myeloid leukemia (AML) in older adults. In the absence of prospective randomized …
acute myeloid leukemia (AML) in older adults. In the absence of prospective randomized …
Older patients with acute myeloid leukemia deserve individualized treatment
DC de Leeuw, GJ Ossenkoppele… - Current oncology reports, 2022 - Springer
Abstract Purpose of Review Treatment of elderly patients with acute myeloid leukemia is a
known challenge for hematologists due to patient diversity, heterogeneous disease biology …
known challenge for hematologists due to patient diversity, heterogeneous disease biology …
Reproducible measurable residual disease detection by multiparametric flow cytometry in acute myeloid leukemia
MA Röhnert, M Kramer, J Schadt, P Ensel, C Thiede… - Leukemia, 2022 - nature.com
Measurable residual disease (MRD) detected by multiparametric flow cytometry (MFC) is
associated with unfavorable outcome in patients with AML. A simple, broadly applicable …
associated with unfavorable outcome in patients with AML. A simple, broadly applicable …
New perspectives in treating acute myeloid leukemia: driving towards a patient-tailored strategy
F Andreozzi, F Massaro, S Wittnebel… - International journal of …, 2022 - mdpi.com
For decades, intensive chemotherapy (IC) has been considered the best therapeutic option
for treating acute myeloid leukemia (AML), with no curative option available for patients who …
for treating acute myeloid leukemia (AML), with no curative option available for patients who …
Transplant outcomes after CPX-351 vs 7+ 3 in older adults with newly diagnosed high-risk and/or secondary AML
GL Uy, LF Newell, TL Lin, SL Goldberg… - Blood …, 2022 - ashpublications.org
Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk
and/or secondary AML | Blood Advances | American Society of Hematology Skip to Main …
and/or secondary AML | Blood Advances | American Society of Hematology Skip to Main …
Secondary acute myeloid leukemia: pathogenesis and treatment
D Capelli, D Menotti, A Fiorentini, F Saraceni… - Exon …, 2022 - exonpublications.com
Secondary acute myeloid leukemia includes acute myeloid leukemia that arises either from
a previous myeloid hematologic disease such as myelodysplastic syndrome, chronic …
a previous myeloid hematologic disease such as myelodysplastic syndrome, chronic …
Measurable residual disease in high-risk acute myeloid leukemia
T Cluzeau, RM Lemoli, J McCloskey, T Cooper - Cancers, 2022 - mdpi.com
Simple Summary Assessment of measurable residual disease (MRD) identifies small
numbers of acute myeloid leukemia (AML) cells that may remain after initiating treatment …
numbers of acute myeloid leukemia (AML) cells that may remain after initiating treatment …