While most naturally occurring DNA and RNA adopt the now quite familiar double-helix
structure, certain sequences can under the appropriate conditions adopt a three-stranded …

Hereditäre Knochentumorerkrankungen sind selten und entwickeln sich in Folge von
Mutationen, die den Zellzyklus (Retinoblastomsyndrom/RB1, Li-Fraumeni-Syndrom/TP53 …

Although many hypotheses have been proposed to explain the strong link between aging
and cancer, the exact mechanisms responsible for the increased frequency of occurrence of …

This chapter reviews clinical and basic science aspects of Werner syndrome (WS), a
heritable human disease that displays features suggestive of premature aging. The …

Abstract Approximately 8–10% of children with cancer have an underlying cancer
predisposition syndrome (CPS). The most commonly mutated genes in the affected patients …

Familiäre Erkrankungen, die zur Bildung von Knochentumoren führen, sind selten. Sie
entwickeln sich im Zusammenhang mit genetischen Alterationen, die den Zellzyklus …

Knochentumoren, die auf dem Boden familiärer genetischer Erkrankungen entstehen, sind
sehr selten. Meist handelt es sich um Enchondrome, Osteochondrome, Osteosarkome oder …

Werner syndrome (WS) is a heredofamilial disorder characterized by clinicopathological
premature aging. In healthy individuals, structural alteration of serum IgG oligosaccharides …

Patella is an uncommon site for the occurrence of bone tumor. Benign tumors are more
common as compared to malignant ones. Osteosarcoma of the patella is a very rare tumor …

Osteosarcoma is a rare tumor in elderly patients. Simultaneous osteosarcoma and thyroid
papillary carcinoma are much rarer, especially in the absence of early radiation or cancer …