Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar Study
C Cutler, SJ Lee, S Arai, M Rotta… - Blood, The Journal …, 2021 - ashpublications.org
Belumosudil, an investigational oral selective inhibitor of Rho-associated coiled-coil–
containing protein kinase 2 (ROCK2), reduces type 17 and follicular T helper cells via …
containing protein kinase 2 (ROCK2), reduces type 17 and follicular T helper cells via …
ROCK2 inhibition with belumosudil (KD025) for the treatment of chronic graft-versus-host disease
M Jagasia, A Lazaryan, CR Bachier… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The rho-associated coiled-coil–containing protein kinase-2 (ROCK2) signaling
pathway regulates the Th17/regulatory T cells balance and controls profibrotic pathways …
pathway regulates the Th17/regulatory T cells balance and controls profibrotic pathways …
Allogeneic stem cell transplantation in multiple myeloma
C Greil, M Engelhardt, J Finke, R Wäsch - Cancers, 2021 - mdpi.com
Simple Summary Due to its graft-versus-myeloma effect, allogeneic hematopoietic stem cell
transplantation (allo-SCT) can enable long-term survival or even cure in carefully selected …
transplantation (allo-SCT) can enable long-term survival or even cure in carefully selected …
Allogeneic transplantation in multiple myeloma—does it still have a place?
G Gahrton, S Iacobelli, L Garderet… - Journal of clinical …, 2020 - mdpi.com
Novel drugs have improved survival for patients with multiple myeloma in recent years.
However, the disease is still fatal. Allogeneic stem cell transplantation (Allo) has proven to …
However, the disease is still fatal. Allogeneic stem cell transplantation (Allo) has proven to …
[PDF][PDF] Guidelines on the diagnosis, investigation and initial treatment of myeloma: a British Society for Haematology/UK Myeloma Forum Guideline.
J Sive, K Cuthill, H Hunter, M Kazmi… - British journal of …, 2021 - ukmyelomasociety.org.uk
Recommendations are based on a review of the literature using Medline, PubMed, Embase,
Central, Web of Science searches from the beginning of 2013 up to July 2019. The following …
Central, Web of Science searches from the beginning of 2013 up to July 2019. The following …
[HTML][HTML] Tandem autologous-autologous versus autologous-allogeneic hematopoietic stem cell transplant for patients with multiple myeloma: long-term follow-up …
Allogeneic hematopoietic cell transplant (HCT) may improve long-term multiple myeloma
(MM) control through the graft-versus-myeloma effect. The Blood and Marrow Transplant …
(MM) control through the graft-versus-myeloma effect. The Blood and Marrow Transplant …
[HTML][HTML] Post-transplantation cyclophosphamide for graft-versus-host disease prophylaxis in multiple myeloma patients who underwent allogeneic hematopoietic cell …
Graft-versus-host disease (GVHD) remains among the major causes of treatment failure in
patients with multiple myeloma (MM) undergoing allogeneic hematopoietic cell …
patients with multiple myeloma (MM) undergoing allogeneic hematopoietic cell …
Current role of allogeneic stem cell transplantation in multiple myeloma
Major progress in the treatment of multiple myeloma has been made in the last several
years. However, myeloma remains incurable and patients with high-risk cytogenetics or …
years. However, myeloma remains incurable and patients with high-risk cytogenetics or …
[HTML][HTML] Summary of the third annual blood and marrow transplant clinical trials network myeloma intergroup workshop on minimal residual disease and immune …
The third annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma
Intergroup Workshop on Minimal Residual Disease and Immune Profiling was held on …
Intergroup Workshop on Minimal Residual Disease and Immune Profiling was held on …
Boosting immunity against multiple myeloma
R Lopes, BV Ferreira, J Caetano, F Barahona… - Cancers, 2021 - mdpi.com
Simple Summary Multiple myeloma is a hematological malignancy arising from the
proliferation of tumor antibody-producing cells in the bone marrow. In this cancer, tumor …
proliferation of tumor antibody-producing cells in the bone marrow. In this cancer, tumor …