The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver responsible
for an increasing number of cancer-related deaths, especially in developing economies of …

Alcohol consumption is a predominant etiological factor in the pathogenesis of chronic liver
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …

Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …

Mouse models are the basis of preclinical and translational research in hepatocellular
carcinoma (HCC). Multiple methods exist to induce tumour formation in mice, including …

On the global scale, primary liver cancer is a major contributor to both cancer incidence and
mortality. It is the sixth most commonly occurring cancer in the world and the third largest …

Primary liver cancers, including hepatocellular carcinoma and intrahepatic
cholangiocarcinoma, are leading causes of cancer-related death worldwide. Recent large …

Alcoholic liver disease (ALD) is a major cause of acute and chronic liver injury. Extensive
evidence has been accumulated on the pathological process of ALD during the past …

Alcoholic liver disease (ALD) includes a broad spectrum of disorders, such as simple
steatosis, cirrhosis, acute alcoholic hepatitis (AH) with or without cirrhosis, and …

DNA damage plays a major role in various pathophysiological conditions including
carcinogenesis, aging, inflammation, diabetes and neurodegenerative diseases. Oxidative …